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青少年在不同风险条件下使用大麻和决策的探索性随访研究。

An exploratory follow-up study of cannabis use and decision-making under various risk conditions within adolescence.

机构信息

Department of Psychology, Center for Children and Families, Florida International University.

Department of Epidemiology, College of Public Health and Health Professions, University of Florida.

出版信息

Neuropsychology. 2023 Jul;37(5):544-556. doi: 10.1037/neu0000897. Epub 2023 Mar 20.

Abstract

OBJECTIVE

Studies examining the associations between decision-making (DM) and cannabis use (CU) often use cross-sectional, adult samples, and composite scores or single tasks to assess DM. The present study explored differential associations between tasks assessing DM under various risk conditions (i.e., ambiguous vs. explicit; gain vs. loss) and CU frequency, CU-related problems, and CU disorder (CUD) onset across a 2-year period within adolescence.

METHOD

Adolescents ( = 401, 90% Hispanic) aged 14-17 at baseline participated in five biannual assessments. CU frequency, CU-related problems, and CUD were assessed using the Drug Use History Questionnaire, Marijuana Problems Scale, and Structured Clinical Interview for , respectively. DM was assessed using the Iowa gambling task (IGT), Game of Dice Task (GDT), and Cups Task. We used latent growth curve modeling to examine bidirectional associations between DM and escalation in CU frequency and CU-related problems, and discrete time survival analyses to determine whether baseline performance across DM tasks predicted CUD onset.

RESULTS

Baseline performance on the GDT predicted greater escalation in CU (β = .200, = .008) and CU-related problems (β = .388, = .035). No other significant associations were found.

CONCLUSIONS

DM under explicit risk may be a more salient risk factor for escalating CU and CU-related problems than DM under ambiguous risk. Deficits in executive functioning could partially explain the results. Findings suggest that neurocognitive development should inform prevention and intervention efforts focused on reducing CU. Given the exploratory nature of the present study, replication of findings is needed. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

摘要

目的

研究决策(DM)和大麻使用(CU)之间关联的研究通常使用横断面、成年样本以及综合评分或单一任务来评估 DM。本研究在青少年时期的 2 年内,探讨了在各种风险条件下(即,模糊与明确;收益与损失)评估 DM 的任务与 CU 频率、CU 相关问题以及 CU 障碍(CUD)发作之间的差异关联。

方法

在基线时年龄为 14-17 岁的青少年(=401,90%为西班牙裔)参与了五次每两年一次的评估。CU 频率、CU 相关问题以及 CUD 使用药物使用史问卷、大麻问题量表和结构临床访谈分别进行评估。DM 使用爱荷华赌博任务(IGT)、骰子游戏任务(GDT)和杯子任务进行评估。我们使用潜在增长曲线模型来检验 DM 和 CU 频率和 CU 相关问题升级之间的双向关联,以及离散时间生存分析来确定 DM 任务的基线表现是否预测 CUD 发作。

结果

GDT 的基线表现预测了 CU(β=0.200,p=.008)和 CU 相关问题(β=0.388,p=.035)的更大升级。没有发现其他显著的关联。

结论

在明确风险下的 DM 可能比在模糊风险下的 DM 更能预测 CU 和 CU 相关问题的升级。执行功能缺陷可以部分解释结果。研究结果表明,神经认知发展应该为旨在减少 CU 的预防和干预努力提供信息。鉴于本研究的探索性质,需要对研究结果进行复制。

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