From the Department of Clinical Pharmacy (Alshabi); from the Department of Pharmacology (Abdel-Wahab, Khateeb, Shaikh), College of Pharmacy; from the Department of Obstetrics and Gynecology (Alshahrani), Faculty of Medicine, Najran University, Najran, and from the Department of Pharmacy Practice (Mannasaheb), College of Pharmacy, AlMaarefa University, Riyadh, Kingdom of Saudi Arabia.
Saudi Med J. 2023 Mar;44(3):314-319. doi: 10.15537/smj.2023.44.3.20220762.
To determine the prevalence of antibiotic use by pregnant women in Najran, Saudi Arabia.
A total of 125 women aged 18 to 45 with a full-term pregnancy participated from October to December 2019. Age, order of current pregnancy, body mass index (BMI), history of miscarriage, and comorbidity were used to estimate antibiotic use.
The majority were Saudis (67.2%), aged 30-35 (39.2%) years, with no history of miscarriage (53.6%), second order of pregnancy (26.4%), and going through weeks 20-25 of pregnancy (21.6%). A total of 26.4% of pregnant women had antibiotic prescriptions in the study population. Pregnant women under 30 years were less likely to receive antibiotics.
The results found an association between maternal age, order of pregnancy and antibiotic use during pregnancy. An association was observed between maternal BMI and the occurrence of adverse drug reactions after antibiotic use. In addition, a history of miscarriage was negatively associated with the use of antibiotics during pregnancy. These predictors of antibiotic administration have the potential to serve as general health indicators and to direct preventative strategies aimed at increasing the rational use of antibiotics.
确定沙特阿拉伯纳季兰孕妇抗生素使用的流行情况。
共有 125 名年龄在 18 至 45 岁的足月妊娠妇女参与了 2019 年 10 月至 12 月的研究。年龄、当前妊娠顺序、体重指数（BMI）、流产史和合并症用于估计抗生素使用情况。
大多数参与者为沙特人（67.2%），年龄在 30-35 岁（39.2%），无流产史（53.6%），第二次妊娠（26.4%），妊娠 20-25 周（21.6%）。研究人群中有 26.4%的孕妇有抗生素处方。年龄小于 30 岁的孕妇不太可能接受抗生素治疗。
结果发现母亲年龄、妊娠顺序和怀孕期间使用抗生素之间存在关联。母体 BMI 与抗生素使用后发生不良反应之间存在关联。此外，流产史与怀孕期间使用抗生素呈负相关。这些抗生素给药的预测因素有可能作为一般健康指标，并指导旨在增加抗生素合理使用的预防策略。
