Ryning F W, McLeod R, Maddox J C, Hunt S, Remington J S
Ann Intern Med. 1979 Jan;90(1):47-9. doi: 10.7326/0003-4819-90-1-47.
Two heart transplant recipients developed toxoplasmosis shortly after surgery. As neither recipient had serologic evidence of exposure to Toxoplasma gondii before transplantation, infection was acquired from an exogenous source. Of the possible modes of transmission of Toxoplasma to the recipients, infection by the oral route or through transfusion of blood or blood products seems remote. Since both heart donors had serologic evidence of recently acquired toxoplasma infection at the time of transplantation and the myocardium is known to be infected with the organism during acute infection, we considered these facts to be a strong implication that the donors' hearts were the most likely source of toxoplasma infection in the recipients.
两名心脏移植受者在术后不久患上了弓形虫病。由于两名受者在移植前均无接触弓形虫的血清学证据,感染是从外部来源获得的。在弓形虫传播给受者的可能途径中,经口途径或通过输血或血液制品感染似乎不太可能。由于两名心脏供者在移植时均有近期获得性弓形虫感染的血清学证据,且已知在急性感染期间心肌会被该生物体感染,我们认为这些事实强烈表明供者的心脏是受者弓形虫感染最可能的来源。