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构建消除弓形虫病的项目 第一部分:引言与概述

Building Programs to Eradicate Toxoplasmosis Part I: Introduction and Overview.

作者信息

Felín Mariangela Soberón, Wang Kanix, Moreira Aliya, Grose Andrew, Leahy Karen, Zhou Ying, Clouser Fatima Alibana, Siddiqui Maryam, Leong Nicole, Goodall Perpetua, Michalowski Morgan, Ismail Mahmoud, Christmas Monica, Schrantz Stephen, Caballero Zuleima, Norero Ximena, Estripeaut Dora, Ellis David, Raggi Catalina, Castro Catherine, Moossazadeh Davina, Ramirez Margarita, Pandey Abhinav, Ashi Kevin, Dovgin Samantha, Dixon Ashtyn, Li Xuan, Begeman Ian, Heichman Sharon, Lykins Joseph, Villalobos-Cerrud Delba, Fabrega Lorena, Montalvo José Luis Sanchez, Mendivil Connie, Quijada Mario R, Fernández-Pirla Silvia, de La Guardia Valli, Wong Digna, de Guevara Mayrene Ladrón, Flores Carlos, Borace Jovanna, García Anabel, Caballero Natividad, Rengifo-Herrera Claudia, de Saez Maria Theresa Moreno, Politis Michael, Wroblewski Kristen, Karrison Theodore, Ross Stephanie, Dogra Mimansa, Dhamsania Vishan, Graves Nicholas, Kirchberg Marci, Mathur Kopal, Aue Ashley, Restrepo Carlos M, Llanes Alejandro, Guzman German, Rebellon Arturo, Boyer Kenneth, Heydemann Peter, Noble A Gwendolyn, Swisher Charles, Rabiah Peter, Withers Shawn, Hull Teri, Su Chunlei, Blair Michael, Latkany Paul, Mui Ernest, Vasconcelos-Santos Daniel Vitor, Villareal Alcibiades, Perez Ambar, Galvis Carlos Andrés Naranjo, Montes Mónica Vargas, Perez Nestor Ivan Cardona, Ramirez Morgan, Chittenden Cy, Wang Edward, Garcia-López Laura Lorena, Muñoz-Ortiz Juliana, Rivera-Valdivia Nicolás, Bohorquez-Granados María Cristina, de-la-Torre Gabriela Castaño, Padrieu Guillermo, Hernandez Juan David Valencia, Celis-Giraldo Daniel, Dávila Juan Alejandro Acosta, Torres Elizabeth, Oquendo Manuela Mejia, Arteaga-Rivera José Y, Nicolae Dan L, Rzhetsky Andrey, Roizen Nancy, Stillwaggon Eileen, Sawers Larry, Peyron Francois, Wallon Martine, Chapey Emanuelle, Levigne Pauline, Charter Carmen, De Frias Migdalia, Montoya Jose, Press Cindy, Ramirez Raymund, Contopoulos-Ioannidis Despina, Maldonado Yvonne, Liesenfeld Oliver, Gomez Carlos, Wheeler Kelsey, Holfels Ellen, Frim David, McLone David, Penn Richard, Cohen William, Zehar Samantha, McAuley James, Limonne Denis, Houze Sandrine, Abraham Sylvie, Piarroux Raphael, Tesic Vera, Beavis Kathleen, Abeleda Ana, Sautter Mari, El Mansouri Bouchra, El Bachir Adlaoui, Amarir Fatima, El Bissati Kamal, de-la-Torre Alejandra, Britton Gabrielle, Motta Jorge, Ortega-Barria Eduardo, Romero Isabel Luz, Meier Paul, Grigg Michael, Gómez-Marín Jorge, Kosagisharaf Jagannatha Rao, Llorens Xavier Sáez, Reyes Osvaldo, McLeod Rima

机构信息

Toxoplasmosis Programs and Initiatives in Panamá, Ciudad de Panamá, Panamá.

Institute for Genomics and Systems Biology, The University of Chicago, Chicago, IL USA.

出版信息

Curr Pediatr Rep. 2022;10(3):57-92. doi: 10.1007/s40124-022-00269-w. Epub 2022 Aug 22.

Abstract

PURPOSE OF REVIEW

Review building of programs to eliminate infections.

RECENT FINDINGS

Morbidity and mortality from toxoplasmosis led to programs in USA, Panama, and Colombia to facilitate understanding, treatment, prevention, and regional resources, incorporating student work.

SUMMARY

Studies foundational for building recent, regional approaches/programs are reviewed. Introduction provides an overview/review of programs in Panamá, the United States, and other countries. High prevalence/risk of exposure led to laws mandating testing in gestation, reporting, and development of broad-based teaching materials about These were tested for efficacy as learning tools for high-school students, pregnant women, medical students, physicians, scientists, public health officials and general public. Digitized, free, smart phone application effectively taught pregnant women about toxoplasmosis prevention. Perinatal infection care programs, identifying true regional risk factors, and point-of-care gestational screening facilitate prevention and care. When implemented fully across all demographics, such programs present opportunities to save lives, sight, and cognition with considerable spillover benefits for individuals and societies.

SUPPLEMENTARY INFORMATION

The online version contains supplementary material available at 10.1007/s40124-022-00269-w.

摘要

综述目的

回顾消除感染项目的建设情况。

最新发现

弓形虫病导致的发病和死亡促使美国、巴拿马和哥伦比亚开展相关项目,以促进对该病的理解、治疗、预防及整合区域资源,并让学生参与其中。

总结

回顾了构建近期区域方法/项目的基础研究。引言部分概述了巴拿马、美国及其他国家的项目。高感染率/暴露风险促使法律规定孕期检测、报告以及编写有关弓形虫病的广泛教材。这些教材作为高中生、孕妇、医学生、医生、科学家、公共卫生官员及普通公众的学习工具,接受了效果测试。数字化的免费智能手机应用有效地向孕妇传授了弓形虫病的预防知识。围产期感染护理项目、识别真正的区域风险因素以及即时妊娠筛查有助于预防和护理。当在所有人群中全面实施时,此类项目为挽救生命、视力和认知提供了机会,对个人和社会具有相当大的溢出效益。

补充信息

网络版包含可在10.1007/s40124-022-00269-w获取的补充材料。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb3a/9395898/ceae844d1759/40124_2022_269_Fig1_HTML.jpg

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