Junaid Khunsa, Afzal Saira, Daood Muhammad, Siddiqui Meha
Department of Community Medicine, King Edward Medical University, Lahore, Pakistan.
J Coll Physicians Surg Pak. 2023 Mar;33(3):325-334. doi: 10.29271/jcpsp.2023.03.325.
Psychiatric morbidity commonly coexists with substance abuse and HIV/AIDS around the globe. This review study aimed to determine the available literature on the prevalence of common substance abuse/use and common mental health illnesses among HIV/AIDS patients worldwide to help policymakers design appropriate strategies to limit extensive substance use and prevent common mental and health illnesses. For the comprehensive literature review, Google Scholar, PubMed Central, Medline, and PakMediNet biomedical databases were searched for original and reviewed studies published in English, from January 2000 to September 2021. Selections of studies and extraction of data from the studies were performed based on quality and inclusion criteria. MedCalc Meta-analysis Software Package version 20.009 was used for data analysis. Out of 103,024 HIV/AIDS patients inspected in 30 studies, 6430 HIV/AIDS patients had pooled prevalence of depression 30.31% (95%CI: 26.028 to 34.786), and 6927 study participants reported the overall current pooled prevalence of any substance use was 25.13% (95%CI: 11.526 to 41.897), respectively. Current alcohol consumption and tobacco smoking are the most common substance abuse, and depression and anxiety are the most common mental health disorders among HIV/AIDS patients. There was no significant publication bias, but substantial heterogeneity was observed in the presented studies. The current systematic review and meta-analysis showed a greater prevalence of substance abuse and mental health illnesses among HIV/AIDS patients than the general population at the global level. Key Words: Substances, Substance use, Substance abuse, Alcohol abuse, Tobacco smoking, HIV/AIDS, Depression, Anxiety, Mental health, HIV/AIDS, Worldwide.
在全球范围内，精神疾病常与药物滥用以及艾滋病毒/艾滋病共存。本综述研究旨在确定全球范围内有关艾滋病毒/艾滋病患者中常见药物滥用/使用情况以及常见精神疾病患病率的现有文献，以帮助政策制定者设计适当策略，限制广泛的药物使用并预防常见的精神和健康疾病。为进行全面的文献综述，检索了谷歌学术、PubMed Central、Medline和PakMediNet生物医学数据库，查找2000年1月至2021年9月以英文发表的原创研究和综述性研究。根据质量和纳入标准进行研究选择和数据提取。使用MedCalc Meta分析软件包版本20.009进行数据分析。在30项研究中检查的103,024名艾滋病毒/艾滋病患者中，6430名艾滋病毒/艾滋病患者的抑郁症合并患病率为30.31%（95%置信区间：26.028至34.786），6927名研究参与者报告任何药物使用的总体当前合并患病率分别为25.13%（95%置信区间：11.526至41.897）。当前饮酒和吸烟是最常见的药物滥用情况，抑郁症和焦虑症是艾滋病毒/艾滋病患者中最常见的精神健康障碍。未观察到明显的发表偏倚，但在所呈现的研究中观察到了显著的异质性。当前的系统综述和荟萃分析表明，在全球范围内，艾滋病毒/艾滋病患者中的药物滥用和精神疾病患病率高于一般人群。关键词：物质、物质使用、药物滥用、酒精滥用、吸烟、艾滋病毒/艾滋病、抑郁症、焦虑症、精神健康、艾滋病毒/艾滋病、全球范围
