Parto-Dezfouli Mohsen, Vezoli Julien, Bosman Conrado Arturo, Fries Pascal
Ernst Strüngmann Institute (ESI) for Neuroscience in Cooperation with Max Planck Society, 60528 Frankfurt, Germany.
Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, 6525 EN Nijmegen, Netherlands.
bioRxiv. 2023 Mar 6:2023.03.06.531093. doi: 10.1101/2023.03.06.531093.
Cognitive functioning requires coordination between brain areas. Between visual areas, feedforward gamma synchronization improves behavioral performance. Here, we investigate whether similar principles hold across brain regions and frequency bands, using simultaneous local field potential recordings from 15 areas during performance of a selective attention task. Short behavioral reaction times (RTs), an index of efficient interareal communication, occurred when occipital areas V1, V2, V4, DP showed gamma synchronization, and fronto-central areas S1, 5, F1, F2, F4 showed beta synchronization. For both area clusters and corresponding frequency bands, deviations from the typically observed phase relations increased RTs. Across clusters and frequency bands, good phase relations occurred in a correlated manner specifically when they processed the behaviorally relevant stimulus. Furthermore, the fronto-central cluster exerted a beta-band influence onto the occipital cluster whose strength predicted short RTs. These results suggest that local gamma and beta synchronization and their inter-regional coordination jointly improve behavioral performance.
认知功能需要脑区之间的协调。在视觉区域之间，前馈伽马同步可改善行为表现。在此，我们利用在执行选择性注意任务期间对15个区域同时进行的局部场电位记录，研究类似的原理是否适用于不同脑区和频段。当枕叶区域V1、V2、V4、DP表现出伽马同步，而额中央区域S1、5、F1、F2、F4表现出贝塔同步时，会出现较短的行为反应时间（RTs），这是区域间有效通信的一个指标。对于这两个区域集群以及相应的频段，偏离典型观察到的相位关系会增加反应时间。在不同集群和频段之间，良好的相位关系以相关的方式出现，特别是当它们处理行为相关刺激时。此外，额中央集群对枕叶集群施加贝塔频段影响，其强度可预测较短的反应时间。这些结果表明，局部伽马和贝塔同步及其区域间协调共同改善行为表现。
