Qin Li-Jiao, Mai Hui-Rong
Department of Hematology and Oncology, Shenzhen Children's Hospital, Shenzhen, Guangdong 518038, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2023 Mar 15;25(3):315-320. doi: 10.7499/j.issn.1008-8830.2210063.
Acute lymphoblastic leukemia (ALL) is the most common malignant neoplastic disease in children. With the continuous improvement in diagnosis and treatment, there has been an increasing number of ALL children who achieve long-term survival after complete remission; however, a considerable proportion of these children have cognitive impairment, which has a serious adverse impact on their learning, employment, and social life. This article reviews the latest research on cognitive impairment in children with ALL from the aspects of the influencing factors, detection techniques, and prevention/treatment methods for cognitive impairment.
急性淋巴细胞白血病(ALL)是儿童最常见的恶性肿瘤性疾病。随着诊断和治疗水平的不断提高,完全缓解后实现长期生存的ALL患儿数量不断增加;然而,这些患儿中有相当一部分存在认知障碍,这对他们的学习、就业和社会生活产生了严重的不利影响。本文从认知障碍的影响因素、检测技术以及预防/治疗方法等方面综述了ALL患儿认知障碍的最新研究进展。