Massachusetts General Hospital, Division of Gastroenterology, Boston, MA, USA.
Clinical Translational Epidemiology Unit, The Mongan Institute, Massachusetts General Hospital, Boston, MA, USA.
Inflamm Bowel Dis. 2023 Oct 3;29(10):1517-1523. doi: 10.1093/ibd/izad049.
Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, are inflammatory diseases of the gastrointestinal tract. The incidence of IBD is increasing in minority populations; however, little is known about the epidemiology and disease characteristics of IBD in Black women.
Our study population included participants in the Black Women's Health Study. Diagnosis of IBD was self-reported through the biennial questionnaires starting at baseline in 1995. We estimated the incidence of IBD according to age and geographic region. A follow-up supplementary questionnaire was also sent to a subset of participants who reported diagnosis of IBD to evaluate the accuracy of self-reported diagnosis and to assess disease characteristics.
Through December 31, 2021, a total of 609 cases of IBD were reported, of which 142 were prevalent at baseline (prevalence, 0.24%), and 467 were incident (crude incidence rate, 33.2/100 000 person-years). The incidence of IBD was highest in the younger than 30 years age group and similar across geographic region. Among the participants who responded to the supplementary questionnaire, 57.1% had confirmed diagnosis of IBD.
In a large prospective cohort of US Black women, we found that the incidence of IBD was similar to previously published estimates in US White women. Future studies should focus on identifying risk factors for IBD in Black individuals in the United States.
炎症性肠病（IBD）包括溃疡性结肠炎和克罗恩病，是胃肠道的炎症性疾病。IBD 在少数族裔人群中的发病率正在增加；然而，关于黑人群体中 IBD 的流行病学和疾病特征知之甚少。
我们的研究人群包括参加黑人妇女健康研究的参与者。IBD 的诊断通过从 1995 年开始的每两年一次的问卷在基线时进行自我报告。我们根据年龄和地理区域估计 IBD 的发病率。还向报告 IBD 诊断的一部分参与者发送了后续补充问卷，以评估自我报告诊断的准确性，并评估疾病特征。
截至 2021 年 12 月 31 日，共报告了 609 例 IBD 病例，其中 142 例为基线时的现患病例（现患率为 0.24%），467 例为新发病例（粗发病率为 33.2/10 万人口年）。IBD 的发病率在 30 岁以下年龄组最高，且在地理区域之间相似。在回答补充问卷的参与者中，57.1% 确诊为 IBD。
在一项针对美国黑人女性的大型前瞻性队列研究中，我们发现 IBD 的发病率与美国白人女性之前发表的估计相似。未来的研究应重点关注在美国识别黑人群体中 IBD 的风险因素。
