Lashch N Y, Erina O V, Nikonova A A, Nikonov A A
Pirogov Russian National Research Medical University, Moscow, Russia.
Kaluga Regional Clinical Hospital, Kaluga, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2023;123(3):110-115. doi: 10.17116/jnevro2023123031110.
Toxoplasmosis is a zoonotic protozoal disease characterized by a chronic course, polymorphism of clinical manifestations, predominant damage to the central nervous system, organs of vision, liver and lungs. The causative agent of the disease is the obligate intracellular parasite Toxoplasma gondii, which circulates widely in the external environment and has a large circle of intermediate hosts. Toxoplasmosis is classified by the method of infection (congenital or acquired), by pathogenesis (acute or chronic), by manifestation (latent or with the manifestation of symptoms). According to the state of the human immune system, the disease can occur without immunodeficiency, while the patient has a chronic lifelong carrier, and with immunodeficiency. People with HIV most commonly present with cerebral toxoplasmosis. The article presents a case of the development of toxoplasmosis in a patient in the absence of a burdened history.
弓形虫病是一种人畜共患的原生动物疾病,其特点是病程慢性、临床表现多样、主要损害中枢神经系统、视觉器官、肝脏和肺部。该疾病的病原体是专性细胞内寄生虫刚地弓形虫,它在外部环境中广泛传播,中间宿主范围广泛。弓形虫病根据感染方式(先天性或后天性)、发病机制(急性或慢性)、表现形式(潜伏性或有症状表现)进行分类。根据人体免疫系统状态,该疾病可在无免疫缺陷的情况下发生,患者成为慢性终身携带者,也可在有免疫缺陷的情况下发生。感染艾滋病毒的人最常出现脑弓形虫病。本文介绍了一例无病史负担患者发生弓形虫病的病例。