Logeswaran Ravichandran, Jeganmohan Masilamani
Department of Chemistry, Indian Institute of Technology Madras, Chennai 600036, Tamil Nadu, India.
J Org Chem. 2023 Apr 7;88(7):4554-4568. doi: 10.1021/acs.joc.3c00036. Epub 2023 Mar 22.
An efficient method for pharmaceutically useful selenoflavones a ruthenium-catalyzed selenylation reaction is demonstrated. The ruthenium-catalyzed selenylation was applied to synthesize diverse alkenyl selenides from simple unsaturated acids/amides and diaryl diselenides. A wide range of differently substituted diaryl diselenides can be applied in this protocol with a good functional group with excellent stereo- and regioselectivity.
一种用于制备药用硒黄酮的有效方法——钌催化的硒化反应得到了证明。钌催化的硒化反应被用于从简单的不饱和酸/酰胺和二芳基二硒醚合成多种烯基硒化物。在该反应体系中，可以使用多种不同取代的二芳基二硒醚，具有良好的官能团兼容性以及出色的立体和区域选择性。
