Weng Zhengyun, Fang Xinyue, He Meicui, Gu Linghui, Lin Jiafu, Li Zheyu, Ma Wenbo
Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province , Sichuan Industrial Institute of Antibiotics, Chengdu University , Chengdu 610052 , P.R. China.
Org Lett. 2019 Aug 16;21(16):6310-6314. doi: 10.1021/acs.orglett.9b02196. Epub 2019 Aug 5.
An efficient ruthenium-catalyzed direct C-H selenylation of aryl acetic amides and esters has been achieved via distal weakly coordination. Notable features of this protocol including broad substrate scope, wide functional group tolerance, and good regioselectivity. In addition, diaryl disulfides were also successfully applied to this reaction under slightly modified conditions.
通过远程弱配位实现了一种高效的钌催化芳基乙酰胺和酯的直接C-H硒化反应。该方法的显著特点包括底物范围广、官能团耐受性好以及区域选择性高。此外，在稍微修改的条件下，二芳基二硫化物也成功应用于该反应。
