Modern Statistical Methods for the Surgeon Scientist: The Clash of Frequentist versus Bayesian Paradigms.

The practice of evidence-based medicine is the result of a multitude of research and trials aimed toward improving health-care outcomes. An understanding of the associated data remains paramount toward optimizing patient outcomes. Medical statistics commonly revolve around frequentist concepts that are convoluted and nonintuitive for nonstatisticians. Within this article, we will discuss frequentist statistics, their limitations, as well as introduce Bayesian statistics as an alternative approach for data interpretation. By doing so, we intend to highlight the importance of correct statistical interpretations through clinically relevant examples while providing a deeper understanding of the underlying philosophies of frequentist and Bayesian statistics.