AdventHealth Translational Research Institute, 301 East Princeton Street, Orlando, FL 32804, USA.
AdventHealth Translational Research Institute, 301 East Princeton Street, Orlando, FL 32804, USA; AdventHealth Diabetes Institute, 2415 North Orange Avenue, Suite 501, Orlando, FL 32804, USA.
Endocrinol Metab Clin North Am. 2023 Jun;52(2):355-375. doi: 10.1016/j.ecl.2022.10.010. Epub 2023 Feb 20.
Diabetes is prevalent in older adults and older adults with diabetes are more likely to have multiple comorbidities. It is, therefore, important to personalize diabetes management in this group. Newer glucose-lowering drugs, including dipeptidyl peptidase-4 inhibitors, sodium-glucose cotransporter 2 inhibitors, and glucagon-like peptide-1 receptor agonists can be safely used in older patients and are preferred choices in many cases due to their safety, efficacy, and low risk of hypoglycemia.
糖尿病在老年人中较为常见，且患有糖尿病的老年人更有可能同时患有多种合并症。因此，对这一群体进行个体化的糖尿病管理非常重要。新型的降血糖药物，包括二肽基肽酶-4 抑制剂、钠-葡萄糖共转运蛋白 2 抑制剂和胰高血糖素样肽-1 受体激动剂，可安全用于老年患者，并且由于其安全性、疗效和低血糖风险低，在许多情况下都是首选。
