Mulualem Biruk, Belay Genetu, Bogale Eyob Ketema
School of Medicine and Health Sciences, Department of Dermatovenereology, Bahir Dar University, Bahir Dar, Amhara, Ethiopia.
Health Promotion and Behavioral Sciences Department, Bahir Dar University, Bahir Dar, Amhara, Ethiopia.
SAGE Open Med. 2023 Mar 17;11:20503121231161191. doi: 10.1177/20503121231161191. eCollection 2023.
To assess the magnitude of chronic osteomyelitis and its associated factors in children at Felege Hiwot Comprehensive Specialized Hospital, Bahir Dar, Ethiopia, in 2022.
A hospital-based cross-sectional study was done between April 15, 2022 and August 15, 2022, in children with an age of 18 years or below, who visited Felege Hiwot Comprehensive Specialized Hospital. A total sample size of 168 participants was involved in the study. The random sampling technique was applied to select the study participants. The data were collected from the patients, their charts, and X-ray requests. The data were cleaned, stored, checked for completeness, and entered into EpiData Version 3.1, which were then exported to SPSS Version 23 for analysis. Descriptive analysis was done, and bivariable and multivariable logistic regression were used for analysis.
The prevalence of chronic osteomyelitis was found to be 86.3%. The tibia and femur were the most commonly involved bones, and metaphyseal involvement was very common. The most common radiological findings were sequestrum (56%) and involucrum (53%). Of the total patients with radiological evidence of chronic osteomyelitis, 16.6% had complications, the most common of which was a pathologic fracture (12.4%). Being male (adjusted odds ratio = 6.162, 95% confidence interval: 1.12-34.147), being over 10 years old (adjusted odds ratio = 4.048, 95% confidence interval: 1.032-15.886), living in a rural area (adjusted odds ratio = 4.046, 95% confidence interval: 1.236-13.364), having a discharging sinus (adjusted odds ratio = 5.237, 95% confidence interval: 1.393-19.693), having a clinical complaint lasting more than 1 year (adjusted odds ratio = 5.189, 95% confidence interval: 1.247-21.588), and a preceding event of trauma (adjusted odds ratio = =10.363, 95% confidence interval: 1.101-97.509) were the factors associated with chronic osteomyelitis.
The prevalence of chronic osteomyelitis is high. In this study, being male, being in the age group above 10 years, having rural residency, having a discharging sinus, having a clinical complaint duration of more than 1 year, and having a preceding event of trauma were the factors associated with chronic osteomyelitis. Therefore, healthcare providers should have a high index of suspicion of chronic osteomyelitis in older male children from rural areas with a chronic discharging sinus following trauma.
评估2022年埃塞俄比亚巴赫达尔市费莱格·希沃特综合专科医院儿童慢性骨髓炎的发病率及其相关因素。
于2022年4月15日至2022年8月15日在费莱格·希沃特综合专科医院对18岁及以下前来就诊的儿童进行了一项基于医院的横断面研究。共有168名参与者纳入该研究。采用随机抽样技术选取研究对象。数据从患者、病历和X光检查申请中收集。对数据进行清理、存储、检查完整性,然后录入EpiData 3.1版本,随后导出至SPSS 23版本进行分析。进行了描述性分析,并采用双变量和多变量逻辑回归进行分析。
发现慢性骨髓炎的患病率为86.3%。胫骨和股骨是最常受累的骨骼,干骺端受累非常常见。最常见的影像学表现是死骨(56%)和骨膜新生骨(53%)。在有慢性骨髓炎影像学证据的所有患者中,16.6%出现了并发症,最常见的是病理性骨折(12.4%)。男性(调整优势比=6.162,95%置信区间:1.12 - 34.147)、10岁以上(调整优势比=4.048,95%置信区间:1.032 - 15.886)居住在农村地区(调整优势比=4.046,95%置信区间:1.236 - 13.364)、有窦道流脓(调整优势比=5.237,95%置信区间:1.393 - 19.693)、临床症状持续超过1年(调整优势比=5.189,95%置信区间:1.247 - 21.588)以及有先前的创伤事件(调整优势比=10.363,95%置信区间:1.101 - 97.509)是与慢性骨髓炎相关的因素。
慢性骨髓炎的患病率很高。在本研究中,男性、10岁以上年龄组、农村居住、有窦道流脓、临床症状持续时间超过1年以及有先前的创伤事件是与慢性骨髓炎相关的因素。因此,医疗服务提供者对于来自农村地区、有慢性窦道流脓且创伤后年龄较大的男性儿童应高度怀疑慢性骨髓炎。