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利用我们共同的非洲起源来理解人类进化与健康。

Leveraging our common African origins to understand human evolution and health.

作者信息

Wonkam Ambroise, Adeyemo Adebowale

机构信息

McKusick-Nathans Institute & Department of Genetic Medicine. Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Center for Research on Genomics and Global Health, National Human Genome Research Institute, The National Institutes of Health, Bethesda, MD, USA.

出版信息

Cell Genom. 2023 Mar 8;3(3):100278. doi: 10.1016/j.xgen.2023.100278.

DOI:10.1016/j.xgen.2023.100278
PMID:36950382
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10025516/
Abstract

In the March 2023 issue of , Fan et al. report whole-genome sequencing across 12 indigenous African populations and analyze local adaptation and evolutionary history. Here, Wonkam and Adeyemo highlight their findings and how this contributes to African and global genomic research.

摘要

在《》2023年3月期,范等人报告了对12个非洲本土人群的全基因组测序,并分析了局部适应性和进化历史。在此,翁卡姆和阿德耶莫强调了他们的发现以及这对非洲和全球基因组研究的贡献。 (原文中“ In the March 2023 issue of ”后面缺少具体期刊名)

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72ec/10025516/0bf6dbcd4bc2/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72ec/10025516/0bf6dbcd4bc2/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72ec/10025516/0bf6dbcd4bc2/gr1.jpg

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本文引用的文献

1
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Cell. 2023 Mar 2;186(5):923-939.e14. doi: 10.1016/j.cell.2023.01.042.
2
Race, Genotype, and Azathioprine Discontinuation : A Cohort Study.种族、基因型和巯嘌呤停用:队列研究。
Ann Intern Med. 2022 Aug;175(8):1092-1099. doi: 10.7326/M21-4675. Epub 2022 Jun 21.
3
Five Priorities of African Genomics Research: The Next Frontier.非洲基因组学研究的五大优先事项:新的前沿领域
狼疮及其他自身免疫性疾病:非洲裔人群中的流行病学以及非洲地区的诊断和管理挑战
J Allergy Clin Immunol Glob. 2024 Jun 1;3(4):100288. doi: 10.1016/j.jacig.2024.100288. eCollection 2024 Nov.
4
Whole genome sequencing reveals population diversity and variation in HIV-1 specific host genes.全基因组测序揭示了HIV-1特异性宿主基因的群体多样性和变异。
Front Genet. 2023 Dec 20;14:1290624. doi: 10.3389/fgene.2023.1290624. eCollection 2023.
Annu Rev Genomics Hum Genet. 2022 Aug 31;23:499-521. doi: 10.1146/annurev-genom-111521-102452. Epub 2022 May 16.
4
Ancient DNA and deep population structure in sub-Saharan African foragers.撒哈拉以南非洲采集狩猎者的古代 DNA 和深度人口结构。
Nature. 2022 Mar;603(7900):290-296. doi: 10.1038/s41586-022-04430-9. Epub 2022 Feb 23.
5
High-depth African genomes inform human migration and health.高深度的非洲基因组信息揭示了人类的迁徙和健康状况。
Nature. 2020 Oct;586(7831):741-748. doi: 10.1038/s41586-020-2859-7. Epub 2020 Oct 28.
6
The major genetic risk factor for severe COVID-19 is inherited from Neanderthals.严重 COVID-19 的主要遗传风险因素来自尼安德特人。
Nature. 2020 Nov;587(7835):610-612. doi: 10.1038/s41586-020-2818-3. Epub 2020 Sep 30.
7
Recovering signals of ghost archaic introgression in African populations.恢复非洲人群中幽灵古渗入信号。
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8
Ancient West African foragers in the context of African population history.古西非觅食者与非洲人口历史背景。
Nature. 2020 Jan;577(7792):665-670. doi: 10.1038/s41586-020-1929-1. Epub 2020 Jan 22.
9
A global reference for human genetic variation.人类遗传变异的全球参考。
Nature. 2015 Oct 1;526(7571):68-74. doi: 10.1038/nature15393.