一名患有胸腺瘤和重症肌无力的患者出现与新冠病毒相关的AMPA受体和CRMP-5自身免疫性脑炎
COVID-19-associated AMPA-R and CRMP-5 autoimmune encephalitis in a patient with thymoma and myasthenia gravis.
作者信息
Raynowska Jenelle, Wu Victoria, Kazer Max, LaBuzetta Jamie Nicole, Ferrey Dominic, Dunn-Pirio Anastasie
机构信息
Department of Neurosciences University of California, San Diego La Jolla California USA.
出版信息
Clin Case Rep. 2023 Mar 19;11(3):e7064. doi: 10.1002/ccr3.7064. eCollection 2023 Mar.
Thymomas are associated with autoimmune disease, most commonly myasthenia gravis, and rarely with autoimmune encephalitis. More recently, viral triggers including COVID-19 have also been implicated in autoimmunity. We present a case of antibody-positive autoimmune encephalitis that developed in the setting of COVID-19 in a patient with thymomatous myasthenia gravis.
胸腺瘤与自身免疫性疾病相关，最常见的是重症肌无力，很少与自身免疫性脑炎相关。最近，包括新冠病毒病（COVID-19）在内的病毒触发因素也被认为与自身免疫有关。我们报告一例抗体阳性的自身免疫性脑炎病例，该病例发生在一名患有胸腺瘤型重症肌无力的患者身上，且处于新冠病毒病感染背景下。
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