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Merkel细胞癌罕见的扁桃体转移：一例报告。

A rare tonsillar metastasis of Merkel cell carcinoma: A case report.

作者信息

Okonkwo Precious C, Henning Ania, Plaza Jose, Agrawal Amit, Contreras Carlo M

机构信息

Kent State University Kent Ohio USA.

The Ohio State Wexner Medical Center Columbus Ohio USA.

出版信息

Clin Case Rep. 2023 Mar 19;11(3):e7063. doi: 10.1002/ccr3.7063. eCollection 2023 Mar.

DOI:10.1002/ccr3.7063
PMID:36950672
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10025251/
Abstract

Merkel cell carcinoma (MCC) metastasis to the tonsil is extremely rare with five published cases. We report the case of a patient with palatine tonsillar MCC metastasis, who presented without oropharyngeal symptoms, which contrast prior reported cases.

摘要

Merkel细胞癌（MCC）转移至扁桃体极为罕见，仅有五例已发表的病例。我们报告一例腭扁桃体MCC转移患者，该患者无口咽症状，这与先前报道的病例不同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5356/10025251/c5475a9b954c/CCR3-11-e7063-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5356/10025251/c103d4e6dad4/CCR3-11-e7063-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5356/10025251/a50fd4a578e8/CCR3-11-e7063-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5356/10025251/c5475a9b954c/CCR3-11-e7063-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5356/10025251/c103d4e6dad4/CCR3-11-e7063-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5356/10025251/a50fd4a578e8/CCR3-11-e7063-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5356/10025251/c5475a9b954c/CCR3-11-e7063-g002.jpg

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本文引用的文献

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Clinical and molecular characteristics associated with response to therapeutic PD-1/PD-L1 inhibition in advanced Merkel cell carcinoma.与晚期 Merkel 细胞癌对治疗性 PD-1/PD-L1 抑制反应相关的临床和分子特征。
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Not Your Typical Tonsil: Metastatic Merkel Cell Carcinoma or Primary Disease?非典型扁桃体：转移性默克尔细胞癌还是原发性疾病？
Cureus. 2021 Apr 21;13(4):e14604. doi: 10.7759/cureus.14604.
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Metastasis of pulmonary adenocarcinoma to the palatine tonsil.肺腺癌转移至腭扁桃体。
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Development of tumor mutation burden as an immunotherapy biomarker: utility for the oncology clinic.肿瘤突变负担作为免疫治疗生物标志物的发展：在肿瘤学临床中的应用。
Ann Oncol. 2019 Jan 1;30(1):44-56. doi: 10.1093/annonc/mdy495.
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Merkel Cell Carcinoma: An Update and Immunotherapy.默克尔细胞癌：最新进展与免疫疗法
Front Oncol. 2018 Mar 6;8:48. doi: 10.3389/fonc.2018.00048. eCollection 2018.
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Frequency and locations of systemic metastases in Merkel cell carcinoma by imaging.通过影像学检查评估默克尔细胞癌全身转移的频率及部位
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