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非激素性积雪草、透明质酸和益生元阴道凝胶治疗复发性外阴阴道念珠菌病的经验:病例研究

Experience With a Non-Hormonal Centella Asiatica, Hyaluronic Acid and Prebiotic-Based Vaginal Gel in Women With Recurrent Vulvovaginal Candidiasis: Case Studies.

作者信息

Amorós Manuela, Mora Palma José Carlos, Esteve María, Salado Mercedes, Macatangga Mónica G, Aguarón Benítez Guadalupe, Luque Pablo, Cortés Javier

机构信息

Departamento de Ginecología y Obstetricia, Policlinic Viladecans, Viladecans, Spain.

Departamento de Ginecología y Obstetricia, Hospital Quirón Sevilla, Sevilla, Spain.

出版信息

Clin Med Insights Case Rep. 2023 Mar 16;16:11795476231161170. doi: 10.1177/11795476231161170. eCollection 2023.

Abstract

Recurrent vulvovaginal candidiasis (RVVC) affects millions of women worldwide, severely impairing their quality of life. Despite the existence of multiple induction and maintenance therapeutic strategies, mainly based on antifungals, relapse rates are still high. Palomacare is a vaginal gel containing, among others, hyaluronic acid and , with repairing and moisturizing properties. A series of 5 clinical cases showed that symptoms improved and even disappeared in women with RVVC receiving Palomacare. None of the patients experienced recurrence after the treatment, having their vaginal health restored, suggesting that the non-hormonal , hyaluronic acid and prebiotic-based gel is effective for preventing RVVC relapse in women of reproductive age.

摘要

复发性外阴阴道念珠菌病(RVVC)影响着全球数百万女性,严重损害她们的生活质量。尽管存在多种诱导和维持治疗策略,主要基于抗真菌药物,但复发率仍然很高。Palomacare是一种阴道凝胶,除其他成分外,还含有透明质酸和,具有修复和保湿特性。一系列5例临床病例显示,接受Palomacare治疗的RVVC女性症状有所改善甚至消失。治疗后所有患者均未复发,阴道健康得以恢复,这表明这种基于非激素、透明质酸和益生元的凝胶对预防育龄女性RVVC复发有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79bc/10026099/0c73bbc342ca/10.1177_11795476231161170-fig1.jpg

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