Okwuasaba F, Ejike C, Parry O
Department of Pharmacology, University of Jos, Nigeria.
J Ethnopharmacol. 1987 Sep-Oct;21(1):55-63. doi: 10.1016/0378-8741(87)90094-8.
Extracts of Portulaca oleracea inhibited twitch tension due to direct (MS) and indirect electrical stimulation via the phrenic nerve (NS) of the rat hemidiaphragm muscle. The rank order of potency was dialysable extract greater than or equal to methanol extract greater than diethylether extract, although all exhibited equal efficacy. The non-dialysable extract did not inhibit twitch tension due to MS or NS. The dialysable, methanol and diethylether extracts inhibited tetanus tension, and attenuated the area under the K+- and caffeine-induced contracture. The contracture induced by nicotinic agonists and K+ on the rectus abdominis muscle was significantly inhibited by these extracts.
马齿苋提取物可抑制大鼠半膈肌因直接（MS）和经膈神经间接电刺激（NS）引起的抽搐张力。效力排序为可透析提取物≥甲醇提取物＞二乙醚提取物，尽管所有提取物的效力相同。不可透析提取物不抑制因MS或NS引起的抽搐张力。可透析、甲醇和二乙醚提取物可抑制强直张力，并减小钾离子和咖啡因诱导挛缩的面积。这些提取物可显著抑制烟碱激动剂和钾离子对腹直肌诱导的挛缩。
