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脉动血流增强膜血浆置换中过滤作用的原理。

Rationale of filtration enhancement in membrane plasmapheresis by pulsatile blood flow.

作者信息

Jaffrin M Y, Ding L H, Gupta B B

机构信息

UACNRS 858, Génie Biologique Université de Technologie de Compiègne BP 233, France.

出版信息

Life Support Syst. 1987 Jul-Sep;5(3):267-71.

PMID:3695585
Abstract

It has been demonstrated in our laboratory that blood flow pulsations enhance plasma filtration rate by 30-60 per cent. The increase in plasmafiltration over the steady flow value is found to be a function of the parameter F. delta V'/QB where F denotes the pulsation frequency, delta V' the volume amplitude of pulsed blood in the filter and QB is the time mean blood flow. The increment in plasma filtration may be related to the increase in time-mean absolute value of shear rate.

摘要

我们实验室已证明,血流脉动可使血浆滤过率提高30%至60%。发现血浆滤过相对于稳定血流值的增加是参数F.δV'/QB的函数,其中F表示脉动频率,δV'表示过滤器中脉动血液的体积振幅,QB是时间平均血流。血浆滤过的增加可能与剪切率时间平均绝对值的增加有关。

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