Reginato A J, Schumacher H R, Jimenez S, Maurer K
Arthritis Rheum. 1979 Feb;22(2):170-6. doi: 10.1002/art.1780220210.
Polyarthritis and tenosynovitis were seen as the presenting complaints in 7 patients with secondary syphilis. Synovial needle biopsy was obtained in 3 cases and showed mild synovitis with infiltration by lymphocytes, plasma cells, and polymorphonuclear leukocytes; vascular congestion; and slightly increased synovial lining cells. In addition, electron microscopy in these synovial membranes showed many necrotic polymorphonuclear leukocytes, much interstitial debris and fibrin, and in 2 patients, bodies suggestive of Treponema pallidum in the interstitium and in vessel lumens.
7例二期梅毒患者以多关节炎和腱鞘炎为首发症状。3例患者进行了滑膜针吸活检，结果显示为轻度滑膜炎，伴有淋巴细胞、浆细胞和多形核白细胞浸润；血管充血；滑膜衬里细胞略有增多。此外，这些滑膜的电子显微镜检查显示有许多坏死的多形核白细胞、大量间质碎片和纤维蛋白，在2例患者的间质和血管腔内可见疑似梅毒螺旋体的物体。
