用于现场爆炸物 SERS 感测的柔性 AuNPs@聚酰亚胺加热芯片的制作。

Fabrication of flexible AuNPs@ polyimide heating chips for in situ explosives SERS sensing in nature samples.

机构信息

Institute of Chemical Materials, China Academy of Engineering Physics, Mianyang, 621900, China; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Material Science and Engineering, Nanjing Tech University, Nanjing, 211816, China; Jiangsu Collaborative Innovation Center for Advanced Inorganic Function Composites, Nanjing Tech University, Nanjing, 211816, China.

Institute of Chemical Materials, China Academy of Engineering Physics, Mianyang, 621900, China.

出版信息

Talanta. 2023 Jun 1;258:124460. doi: 10.1016/j.talanta.2023.124460. Epub 2023 Mar 21.

DOI:10.1016/j.talanta.2023.124460

PMID:36958100

Abstract

In this study, highly sensitive flexible AuNPs@ polyimide SERS heating chips (APHC) were fabricated for in situ collecting and detecting TNT. Large-scale AuNPs arrays were synthesized by liquid-liquid interface self-assembly and transferred to polyimide heating film as SERS substrates. 4-ATP and AgNPs functionalized on APHC were used as capture means and signal amplifiers, combining with TNT to form the AuNPs-TNT-AgNPs "sandwich" structure. This flexible APHC chip showed high sensitivity as enhancement factor was 5.5×10, and good repeatability and stability (RSD<10%). It was applied to detect TNT solutions with a low concentration of 10 M, and showed a good linear response in the range from 10 to 10 M (R = 0.986). In addition, the detection method also had good selectivity and no response to various TNT analogs. More important, combing with the thermal enrichment strategy, TNT dispersed in environmental samples such as soil, fruit and clothing would be enriched as vapor then collected and detected by APHC. This APHC device shows great potential for in situ sensing platforms, due to its sensitivity, high efficiency, and excellent portability.

摘要

在这项研究中，制备了高灵敏度的柔性 AuNPs@聚酰亚胺 SERS 加热芯片（APHC），用于原位收集和检测 TNT。通过液-液界面自组装合成了大规模的 AuNPs 阵列，并将其转移到聚酰亚胺加热膜上作为 SERS 基底。APHC 上的 4-ATP 和 AgNPs 被用作捕获手段和信号放大器，与 TNT 结合形成 AuNPs-TNT-AgNPs“三明治”结构。这种柔性 APHC 芯片表现出很高的灵敏度，增强因子为 5.5×10，具有良好的重复性和稳定性（RSD<10%）。它被应用于检测浓度低至 10 M 的 TNT 溶液，在 10 到 10 M 的范围内表现出良好的线性响应（R=0.986）。此外，该检测方法还具有良好的选择性，对各种 TNT 类似物没有响应。更重要的是，结合热富集策略，可将分散在土壤、水果和衣物等环境样品中的 TNT 作为蒸气进行富集，然后通过 APHC 进行收集和检测。由于其灵敏度高、效率高、便携性好，这种 APHC 器件在原位传感平台方面具有很大的应用潜力。