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四通道 Wada 试验:在癫痫手术前,采用基于立体定向脑电图(SEEG)的电刺激、高频活动和相位振幅耦合的联合定位,以补充传统 Wada 试验和功能磁共振成像(fMRI)。

Four-Way Wada: SEEG-based mapping with electrical stimulation, high frequency activity, and phase amplitude coupling to complement traditional Wada and functional MRI prior to epilepsy surgery.

机构信息

Children's Healthcare of Atlanta, Atlanta, GA, USA; Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.

Nihon Kohden, Irvine, CA, USA.

出版信息

Epilepsy Res. 2023 May;192:107129. doi: 10.1016/j.eplepsyres.2023.107129. Epub 2023 Mar 21.


DOI:10.1016/j.eplepsyres.2023.107129
PMID:36958107
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11008564/
Abstract

Presurgical evaluation of refractory epilepsy involves functional investigations to minimize postoperative deficit. Assessing language and memory is conventionally undertaken using Wada and fMRI, and occasionally supplemented by data from invasive intracranial electroencephalography, such as electrical stimulation, corticortical evoked potentials, mapping of high frequency activity and phase amplitude coupling. We describe the comparative and complementary role of these methods to inform surgical decision-making and functional prognostication. We used Wada paradigm to standardize testing across all modalities. Postoperative neuropsychological testing confirmed deficit predicted based on these methods.

摘要

术前评估难治性癫痫需要进行功能研究以最大程度地减少术后缺陷。传统上,使用 Wada 测试和 fMRI 评估语言和记忆,偶尔还会补充来自侵袭性颅内脑电图的数据,例如电刺激、皮质诱发电位、高频活动和相位振幅耦合的映射。我们描述了这些方法的比较和互补作用,以告知手术决策和功能预后。我们使用 Wada 范式使所有模式的测试标准化。术后神经心理学测试证实了这些方法预测的缺陷。

相似文献

[1]
Four-Way Wada: SEEG-based mapping with electrical stimulation, high frequency activity, and phase amplitude coupling to complement traditional Wada and functional MRI prior to epilepsy surgery.

Epilepsy Res. 2023-5

[2]
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[3]
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[4]
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[5]
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[6]
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[7]
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[8]
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[9]
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[10]
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引用本文的文献

[1]
Can memory mapping via stereo-electroencephalography stimulation predict post-operative memory outcomes? A case report.

J Neurol. 2025-8-25

[2]
Neural (re)organisation of language and memory: implications for neuroplasticity and cognition.

J Neurol Neurosurg Psychiatry. 2025-4-10

[3]
Mapping Cognition in Epilepsy: From the Lab to the Clinic.

Epilepsy Curr. 2024-11-21

[4]
SEEG4D: a tool for 4D visualization of stereoelectroencephalography data.

Front Neuroinform. 2024-9-3

[5]
Ictal Central Apnea Is Predictive of Mesial Temporal Seizure Onset: An Intracranial Investigation.

Ann Neurol. 2024-5

本文引用的文献

[1]
Visual speech differentially modulates beta, theta, and high gamma bands in auditory cortex.

Eur J Neurosci. 2021-11

[2]
Cognitive and Emotional Mapping With SEEG.

Front Neurol. 2021-4-12

[3]
High-gamma modulation language mapping with stereo-EEG: A novel analytic approach and diagnostic validation.

Clin Neurophysiol. 2020-12

[4]
Electrical stimulation sensorimotor mapping with stereo-EEG.

Clin Neurophysiol. 2020-8

[5]
Stimulation Mapping Using Stereoelectroencephalography: Current and Future Directions.

Front Neurol. 2020-5-12

[6]
Relationship between direct cortical stimulation and induced high-frequency activity for language mapping during SEEG recording.

J Neurosurg. 2021-3-1

[7]
Phase synchronization varies systematically with linguistic structure composition.

Philos Trans R Soc Lond B Biol Sci. 2019-12-16

[8]
Phase-amplitude coupling between theta and gamma oscillations adapts to speech rate.

Ann N Y Acad Sci. 2019-4-24

[9]
Language mapping using electrocorticography versus stereoelectroencephalography: A case series.

Epilepsy Behav. 2018-7

[10]
Getting the best outcomes from epilepsy surgery.

Ann Neurol. 2018-4-10

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