动态调节过程中巩膜变化的量化

Quantification of scleral changes during dynamic accommodation.

作者信息

Cabeza-Gil Iulen, Manns Fabrice, Calvo Begoña, Ruggeri Marco

机构信息

Aragón Institute of Engineering Research (i3A), University of Zaragoza, Spain.

Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA; Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, FL, USA.

出版信息

Exp Eye Res. 2023 May;230:109441. doi: 10.1016/j.exer.2023.109441. Epub 2023 Mar 22.

DOI:10.1016/j.exer.2023.109441

PMID:36958428

Abstract

The mechanics of accommodation is a complex process that involves multiple intraocular ocular structures. Recent studies suggest that there is deformation of the sclera during accommodation that may also play a role in accommodation, influencing ciliary muscle contraction and contributing to the accommodative response. However, the type and magnitude of the deformations measured varies significantly across studies. We present high-resolution synchronous OCT measurements of the anterior sclera contour and thickness and lens thickness acquired in real-time during accommodative responses to 4D step stimuli. The lens thickness was used as an assessment of objective accommodation. No changes in nasal and temporal anterior scleral contour and scleral thickness were found during accommodation within the precision of our measurements. Our results demonstrate that there are no significant scleral deformations during accommodation.

摘要

调节机制是一个复杂的过程，涉及多个眼内结构。最近的研究表明，在调节过程中巩膜会发生变形，这可能也在调节中发挥作用，影响睫状肌收缩并促成调节反应。然而，不同研究中测量到的变形类型和程度差异很大。我们展示了在对4D阶梯刺激的调节反应过程中实时获取的前巩膜轮廓、厚度以及晶状体厚度的高分辨率同步光学相干断层扫描（OCT）测量结果。晶状体厚度被用作客观调节的评估指标。在我们测量精度范围内，调节过程中未发现鼻侧和颞侧前巩膜轮廓及巩膜厚度有变化。我们的结果表明，调节过程中巩膜无明显变形。