Abdul Rahman Nargis, Ghani Mansoor, Kausar Samina, Sadiqa Ayesha, Khalid Asma
Nursing, Institute of Nursing, University of Health Sciences, Lahore, PAK.
Internal Medicine, University of Health Sciences, Lahore, PAK.
Cureus. 2023 Feb 19;15(2):e35184. doi: 10.7759/cureus.35184. eCollection 2023 Feb.
In the recent past, the procedure of hemodialysis has frequently been opted for patients with end-stage renal disease (ESRD) around the globe. In such patients, the concern of sexual dysfunction is highly prevalent, which causes psychological as well as social deterioration in these patients. Wretchedly, this issue has been ignored in developing countries like Pakistan because of social and cultural constraints. Objectives: The aim was to measure and compare Female Sexual Functions of Dialysis (FSFI) scores among three comparative groups: healthy controls, pre-dialysis patients, and hemodialysis patients.
A comparative cross-sectional study was carried out with 60 females aged 22-50 years in which 20 were healthy (controls) and 40 were patients with ESRD; of these 40, 20 were taking only oral medicines (pre-dialysis) and 20 were also receiving hemodialysis (hemodialysis). Married women who could read Urdu and were living with live spouses were included, and those with any psychological or psychiatric illness were excluded. Data was collected through a Likert-scaled questionnaire, Urdu translation of the FSFI questionnaire, and scores of each domain were analyzed. Single-tail one-way ANOVA was used to observe the significant difference among the three comparative groups.
A strong statistical difference was observed among the hemodialysis, pre-dialysis, and healthy control groups when these three study groups were compared for the mean scores of all related domains of FSFI questtionarie. In each female sexual domain, i.e. Desire, Arousal, Lubrication, Orgasm, Satisfaction, and Pain, the diseased groups (pre-dialysis and hemodialysis) showed lower sexual scores than the healthy group. The lowest scores were observed in the pre-dialysis group (16.4 ± 6.8) and the highest were noticed in the healthy group (29.9 ± 1.8); the hemodialysis group (23.3 ± 5.0) expressed a moderate pattern of scores in each sexual domain.
ESRD female patients who were receiving hemodialysis along with routine oral medications showed improved sexual physiology (with better FSFI scores) compared to those who were without hemodialysis.
近年来,全球范围内终末期肾病(ESRD)患者经常选择血液透析治疗。在这类患者中,性功能障碍问题非常普遍,这会导致患者心理和社会状况恶化。遗憾的是,由于社会和文化限制,在巴基斯坦等发展中国家,这个问题一直被忽视。目的:旨在测量和比较三个比较组(健康对照组、透析前患者和血液透析患者)的女性性功能指数(FSFI)得分。
对60名年龄在22至50岁的女性进行了一项比较性横断面研究,其中20名是健康女性(对照组),40名是ESRD患者;在这40名患者中,20名仅服用口服药物(透析前),20名同时接受血液透析(血液透析组)。纳入能阅读乌尔都语且与在世配偶共同生活的已婚女性,排除患有任何心理或精神疾病的女性。通过李克特量表问卷、FSFI问卷的乌尔都语翻译收集数据,并分析每个领域的得分。采用单尾单向方差分析观察三个比较组之间的显著差异。
当比较血液透析组、透析前组和健康对照组在FSFI问卷所有相关领域的平均得分时,观察到了强烈的统计学差异。在每个女性性功能领域,即性欲、性唤起、润滑、性高潮、满意度和疼痛方面,患病组(透析前组和血液透析组)的性功能得分均低于健康组。透析前组得分最低(16.4±6.8),健康组得分最高(29.9±1.8);血液透析组(23.3±5.0)在每个性功能领域的得分呈中等水平。
与未接受血液透析的ESRD女性患者相比,同时接受常规口服药物和血液透析的ESRD女性患者性功能生理状况有所改善(FSFI得分更高)。