磁共振 T2 成像在子宫内膜癌与良性子宫内膜病变鉴别诊断中的作用。
Role of T2 mapping of magnetic resonance imaging in the differentiation of endometrial cancer and benign endometrial lesions.
机构信息
Department of Radiology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Shandong, China.
Department of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Shandong, China.
出版信息
Diagn Interv Radiol. 2023 Jan 31;29(1):183-189. doi: 10.4274/dir.2021.21884. Epub 2022 Dec 28.
PURPOSE
The T2 mapping of magnetic resonance imaging (MRI) in endometrial cancer (EC), benign endometrial lesions (BELs), and normal endometrium (NE) has rarely been reported. This study aimed to determine the T2 values of MRI in EC, BELs, and NE to investigate whether the T2 values can differentiate them and to assess the aggressiveness of EC.
METHODS
In total, 73 patients [EC, 51 (age, 57.4 ± 5.4 years); BELs, 22 (age, 57.8 ± 11.8 years)] and 23 normal volunteers (age, 56.1 ± 6.6 years) were included. The T2 values of MRI of the EC (type I and II), BEL, and NE groups were described and compared. The relationships between the T2 values of MRI in EC and the pathological characteristics [International Federation of Gynecology and Obstetrics (FIGO) stage and grade] were analyzed.
RESULTS
The median T2 values of NE, BEL, and EC were 197.5 (142.9-324.0) ms, 131.1 (103.2-247.9) ms, and 103.0 (71.6-243.5) ms ( < 0.001), respectively. The median T2 values of type I and type II EC were 100.8 (71.62-130.44) ms and 125.7 (119.7-243.5) ms, respectively. There were significant differences in the T2 values among the NE, BEL, type I EC, and type II EC groups ( < 0.001) except for between the type II EC and BEL groups ( = 0.938). The T2 value of MRI in type I EC was significantly lower than that in type II EC ( = 0.001). There were no significant differences in patients with type I EC having different FIGO stages ( = 0.273) or tumor grades ( = 0.686).
CONCLUSION
T2 mapping of MRI has the potential to quantitatively differentiate between EC, BELs, and NE as well as between type I and type II EC.
目的
磁共振成像（MRI）T2 映射在子宫内膜癌（EC）、良性子宫内膜病变（BELs）和正常子宫内膜（NE）中很少有报道。本研究旨在确定 MRI 在 EC、BELs 和 NE 中的 T2 值，以探讨 T2 值是否可以区分它们，并评估 EC 的侵袭性。
方法
共纳入 73 例患者[EC，51 例（年龄，57.4±5.4 岁）；BELs，22 例（年龄，57.8±11.8 岁）]和 23 名正常志愿者（年龄，56.1±6.6 岁）。描述并比较了 EC（I 型和 II 型）、BEL 和 NE 组的 MRI T2 值。分析了 MRI 中 EC 的 T2 值与病理特征[国际妇产科联合会（FIGO）分期和分级]之间的关系。
结果
NE、BEL 和 EC 的中位数 T2 值分别为 197.5（142.9-324.0）ms、131.1（103.2-247.9）ms 和 103.0（71.6-243.5）ms（<0.001）。I 型和 II 型 EC 的中位数 T2 值分别为 100.8（71.62-130.44）ms 和 125.7（119.7-243.5）ms。除了 II 型 EC 与 BEL 组之间（=0.938），NE、BEL、I 型 EC 和 II 型 EC 组之间的 T2 值存在显著差异（<0.001）。I 型 EC 的 MRI T2 值明显低于 II 型 EC（=0.001）。I 型 EC 患者的不同 FIGO 分期（=0.273）或肿瘤分级（=0.686）之间无显著差异。
结论
MRI 的 T2 映射具有定量区分 EC、BELs 和 NE 以及 I 型和 II 型 EC 的潜力。
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