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老年患者因慢性尿潴留行经尿道前列腺切除术的手术结果及处理算法的提出。

Surgical Outcomes for Elderly Patients Undergoing Transurethral Resection of the Prostate for Chronic Urinary Retention and Proposal of a Management Algorithm.

机构信息

Urology Department, University Hospital Southampton, Southampton, United Kingdom.

Urology Department, Bristol Royal Infirmary, Bristol, United Kingdom.

出版信息

J Endourol. 2023 May;37(5):581-586. doi: 10.1089/end.2022.0654. Epub 2023 May 5.

Abstract

Chronic urinary retention (CUR) is a major problem in elderly patients and leads to high levels of morbidity. CUR can be treated surgically with transurethral resection of the prostate (TURP), but surgery is frequently avoided in elderly patients due to increased perioperative risks and the presence of detrusor underactivity, which can lead to surgical failure. We report on contemporary outcomes for catheterized elderly patients undergoing TURP from a high-volume university teaching hospital. Catheterized patients 80 years of age and older undergoing TURP for CUR at a university teaching hospital between 2012 and 2020 (9 years) were eligible. Those with neurogenic bladder, urethral stricture, or prior TURP were excluded. Surgical success was defined as being catheter free at 3- and 12-month follow-up. Statistical analysis was performed using the Chi-squared test for grouped data and logistic regression modeling for continuous data. A total of 147 patients were included and underwent TURP. Of these, 118 (80.3%) were completely catheter free or using intermittent self-catheterization at initial 3-month follow-up. One hundred seventeen (79.6%) remained catheter free at 1-year follow-up. Postvoid residual >1500 mL before TURP ( = 0.017); age ≥90 ( = 0.0067); and World Health Organization performance status ≥3 ( < 0.00001) were all identified as independent risk factors for surgical failure. A selected subset of patients excluding these risk factors showed overall catheter-free rates of 88.8% at 3-month follow-up. Early and late complications were noted in 6.8% and 2.7% of patients. Our contemporary series demonstrate high rates of successful postoperative voiding for selected elderly patients after TURP, with catheter-free rates at 12 months of 88.8%. Overall complication rate was 9.5%, which may be justified given the alternative morbidity of long-term catheterization. TURP remains an efficacious and cost-effective treatment for selected elderly patients who are catheterized for CUR.

摘要

慢性尿潴留(CUR)是老年患者的一个主要问题,会导致高发病率。CUR 可以通过经尿道前列腺切除术(TURP)进行手术治疗,但由于围手术期风险增加和逼尿肌活动低下,老年患者通常避免手术,这可能导致手术失败。我们报告了一家高容量大学教学医院接受 TURP 治疗的导尿老年患者的当代治疗结果。

在大学教学医院接受 TURP 治疗 CUR 的 80 岁及以上导尿患者符合条件。排除神经源性膀胱、尿道狭窄或既往 TURP 患者。手术成功的定义为在 3 个月和 12 个月的随访时无导管。使用卡方检验进行分组数据的统计分析,使用逻辑回归模型进行连续数据的统计分析。

共纳入 147 例患者,并进行了 TURP。其中,118 例(80.3%)在初始 3 个月随访时完全无导管或间歇性自行导尿。117 例(79.6%)在 1 年随访时仍无导管。TURP 前残余尿量>1500ml( = 0.017);年龄≥90 岁( = 0.0067);以及世界卫生组织表现状态≥3( < 0.00001)均被确定为手术失败的独立危险因素。排除这些危险因素的一组选定患者,在 3 个月随访时总体无导管率为 88.8%。6.8%和 2.7%的患者分别出现早期和晚期并发症。

我们的当代系列研究表明,对于接受 TURP 治疗的选定老年患者,术后排尿成功率较高,12 个月时无导管率为 88.8%。总并发症发生率为 9.5%,鉴于长期留置导管的替代发病率,这可能是合理的。TURP 仍然是一种有效的、具有成本效益的治疗方法,适用于因 CUR 而导尿的选定老年患者。

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