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津巴布韦耐药结核病患者有条件现金转移支付的覆盖范围和效果:一项混合方法研究。

Coverage and effectiveness of conditional cash transfer for people with drug resistant tuberculosis in Zimbabwe: A mixed methods study.

作者信息

Timire Collins, Sandy Charles, Ferrand Rashida A, Mubau Regina, Shiri Peter, Mbiriyawanda Obert, Mbiba Fredrick, Houben Rein M G J, Pedrazzoli Debora, Bond Virginia, Foster Nicola, Kranzer Katharina

机构信息

Department of Clinical Research, London School of Hygiene & Tropical Medicine (LSHTM), London, United Kingdom.

National TB Control Programme, Ministry of Health and Child Care, Harare, Zimbabwe.

出版信息

PLOS Glob Public Health. 2022 Dec 21;2(12):e0001027. doi: 10.1371/journal.pgph.0001027. eCollection 2022.

Abstract

The End TB strategy recommends social protection to mitigate socio-economic impacts of tuberculosis. Zimbabwe started implementing a conditional cash transfer (CCT) programme for people on drug resistant tuberculosis (DR-TB) treatment in 2013. We aimed to determine the proportion of people receiving CCT and effectiveness of CCT in improving treatment outcomes, explore their experiences with registering for CCT and understand the impact of CCT from the perspective of beneficiaries. Data from 2014-2021 were extracted from TB registers and CCT payment records within the National TB Programme. Sixteen in-depth interviews were conducted with people who were completing treatment or had completed treatment within two months. Poisson regression, adjusted for province, year of treatment, age and sex was used to investigate associations between receiving CCT and successful treatment outcomes among people who were in DR-TB care for ≥3 months after treatment initiation. Qualitative data were analyzed using thematic analysis. A total of 481 people were included in the quantitative study. Of these, 53% (254/481) received CCT at some point during treatment. People who exited DR-TB care within three months were 73% less likely to receive CCT than those who did not (prevalence ratio (PR) = 0.27 [95%CI: 0.18-0.41]). Among those who were alive and in care three months after treatment initiation, CCT recipients were 32% more likely to have successful outcomes than those who did not (adjusted PR = 1.32, [95%CI: 1.00-1.75]). Qualitative results revealed lack of knowledge about availability of CCT among people with DR-TB and missed opportunities by healthcare providers to provide information about availability of CCT. Delays and inconsistencies in disbursements of CCT were frequent themes. CCT were associated with successful treatment outcomes. Improvements in coverage, timeliness and predictability of disbursements are recommended.

摘要

终结结核病战略建议实施社会保护,以减轻结核病对社会经济的影响。津巴布韦于2013年开始为接受耐多药结核病治疗的患者实施有条件现金转移支付(CCT)计划。我们旨在确定接受CCT的患者比例以及CCT在改善治疗结果方面的有效性,探索他们注册CCT的经历,并从受益人的角度了解CCT的影响。从国家结核病计划中的结核病登记册和CCT支付记录中提取了2014年至2021年的数据。对正在完成治疗或在两个月内完成治疗的患者进行了16次深入访谈。使用泊松回归分析,并对省份、治疗年份、年龄和性别进行了调整,以研究在开始治疗后接受耐多药结核病治疗≥3个月的患者中,接受CCT与成功治疗结果之间的关联。使用主题分析法对定性数据进行了分析。定量研究共纳入481人。其中,53%(254/481)的患者在治疗期间的某个时间点接受了CCT。在三个月内结束耐多药结核病治疗的患者接受CCT的可能性比未结束治疗的患者低73%(患病率比(PR)=0.27[95%CI:0.18 - 0.41])。在开始治疗三个月后仍存活并接受治疗的患者中,接受CCT的患者成功治疗的可能性比未接受CCT的患者高32%(调整后的PR = 1.32,[95%CI:1.00 - 1.75])。定性结果显示,耐多药结核病患者对CCT的可用性缺乏了解,医疗服务提供者也错失了提供CCT可用性信息的机会。CCT支付的延迟和不一致是常见问题。CCT与成功的治疗结果相关。建议提高支付的覆盖率、及时性和可预测性。

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