Department of Chemistry, Laboratory of Analytical Chemistry, Aristotle University of Thessaloniki, Thessaloniki, Greece.
J Sep Sci. 2023 Jun;46(12):e2300081. doi: 10.1002/jssc.202300081. Epub 2023 Apr 3.
Bisphenols are used as monomers in the production of plastic materials, and they are likely to be detected in food contact materials. Due to their migration from these plastic packaging materials into food and beverages, the organoleptic properties of the products are changing and plenty of harmful effects on human health are caused, especially if consumers are exposed to higher levels of bisphenols than those established by legislation. However, because of their trace-level presence, their determination into food and beverage matrices is rather difficult. For this reason, sensitive, simple, rapid, and green methods are required to extract and preconcentrate the analytes of interest. Effective and representative tests are required as well, to evaluate the migration of bisphenols from plastic materials under realistic usage conditions. This review provides a detailed background of bisphenol A chemistry and legislation. Furthermore, it refers to bisphenol A migration test procedures and the recent advances of the last decade in the extraction of bisphenols from various matrices by using different sample preparation techniques prior to their chromatographic determination.
双酚类物质被用作生产塑料材料的单体，并且很可能会在食品接触材料中被检测到。由于它们从这些塑料包装材料迁移到食品和饮料中，产品的感官特性正在发生变化，并对人类健康造成了大量的有害影响，特别是如果消费者接触到的双酚类物质水平高于立法规定的水平。然而，由于其痕量存在，将其测定到食品和饮料基质中是相当困难的。因此，需要敏感、简单、快速和绿色的方法来提取和预浓缩感兴趣的分析物。此外，还需要有效的和有代表性的测试方法，以评估在实际使用条件下塑料材料中双酚类物质的迁移情况。这篇综述提供了双酚 A 化学和法规的详细背景。此外，它还提到了双酚 A 迁移测试程序，以及过去十年中在使用不同的样品前处理技术提取各种基质中的双酚类物质，然后进行色谱测定方面的最新进展。
