Klasser Gary D, Goulet Jean-Paul, Moreno-Hay Isabel
Department of Diagnostic Sciences, School of Dentistry, Louisiana State University Health Sciences Center, 1100 Florida Avenue, Box #8, New Orleans, LA 70119, USA.
Pavillon de Médecine Dentaire, Université Laval, 2420 Rue de La Terrasse, Québec, G1V 0A6, Canada.
Dent Clin North Am. 2023 Apr;67(2):211-225. doi: 10.1016/j.cden.2022.12.001. Epub 2023 Feb 1.
Designing classification systems and developing diagnostic criteria for temporomandibular disorders is difficult. An appreciation of the utility and applicability of these entities requires an understanding of the importance of each, the differences between the two, and how they may be optimally operationalized for both clinical and research activities in light of their inherent advantages and limitations. In addition, consideration for adopting newer approaches, such as following ontological and precision-based medicine principles, accounting for genetics/epigenetic and neurobiological factors, and the inclusion of biomarkers will potentially result in more thorough and comprehensive classification systems and diagnostic criteria.
设计颞下颌关节紊乱病的分类系统并制定诊断标准颇具难度。要认识到这些疾病的实用性和适用性，需要理解每一项的重要性、两者之间的差异，以及鉴于其固有的优势和局限性，如何针对临床和研究活动对它们进行最佳操作。此外，考虑采用更新的方法，如遵循本体论和精准医学原则、考虑遗传学/表观遗传学和神经生物学因素以及纳入生物标志物，可能会产生更全面、更综合的分类系统和诊断标准。
