Giannos Panagiotis, Prokopidis Konstantinos, Candow Darren G, Forbes Scott C, Celoch Kamil, Isanejad Masoud, Pekovic-Vaughan Vanja, Witard Oliver C, Gabriel Brendan M, Scott David
Department of Life Sciences, Faculty of Natural Sciences, Imperial College London, UK; Society of Meta-research and Biomedical Innovation, London, UK.
Society of Meta-research and Biomedical Innovation, London, UK; Department of Musculoskeletal Biology, Institute of Life Course and Medical Sciences, University of Liverpool, UK.
Sleep Med. 2023 May;105:78-84. doi: 10.1016/j.sleep.2023.03.013. Epub 2023 Mar 15.
Habitual declines in sleep duration and increased rates of obesity are public health concerns worldwide. Accumulating evidence suggests a prominent link between reduced sleep duration and weight gain. Our cross-sectional study investigated the relationship between sleep duration and body fat distribution in US adults. We extracted data for 5151 participants (2575 men and 2576 women) aged 18-59 years from the US National Health and Nutrition Examination Survey 2011-2012 and 2013-2014. Weekday or workday night-time sleep duration was estimated using an in-home interview questionnaire. Dual-energy x-ray absorptiometry scans were used to determine regional body fat mass (arms, legs, trunk [android and gynoid], and abdominal [subcutaneous and visceral]). Multiple linear regression and restricted cubic spline analyses were performed after adjusting for several demographic, anthropometric, and nutritional covariates. There was a significant negative association between sleep duration and visceral fat mass overall (β: -12.139, P < 0.001) and by sex (men: β: -10.096, P < 0.001; women: β: -11.545, P = 0.038), after adjusting for age, ethnicity, body mass index, total body fat mass, daily energy and alcohol intake, sleep quality and sleep disorder status. Sleep duration and visceral fat appeared to plateau at ≥ 8 h of daily sleep. Sleep duration is negatively associated with visceral fat mass accumulation during adulthood with possibly no benefits beyond 8 h of sleep per day. Mechanistic and prospective studies are required to confirm the effect of sleep duration on visceral adiposity and determine its causes.
睡眠时长的习惯性减少和肥胖率的上升是全球范围内的公共卫生问题。越来越多的证据表明，睡眠时长减少与体重增加之间存在显著联系。我们的横断面研究调查了美国成年人睡眠时长与体脂分布之间的关系。我们从2011 - 2012年和2013 - 2014年的美国国家健康与营养检查调查中提取了5151名年龄在18 - 59岁之间的参与者（2575名男性和2576名女性）的数据。工作日或工作夜晚的睡眠时长通过家庭访谈问卷进行估算。采用双能X线吸收法扫描来确定身体各部位的脂肪量（手臂、腿部、躯干[男性型和女性型]以及腹部[皮下和内脏]）。在对若干人口统计学、人体测量学和营养协变量进行调整后，进行了多元线性回归和受限立方样条分析。在调整年龄、种族、体重指数、全身脂肪量、每日能量和酒精摄入量、睡眠质量和睡眠障碍状态后，总体上睡眠时长与内脏脂肪量之间存在显著负相关（β：-12.139，P < 0.001），按性别分析也是如此（男性：β：-10.096，P < 0.001；女性：β：-11.545，P = 0.038）。睡眠时长与内脏脂肪在每日睡眠≥8小时时似乎趋于平稳。成年期睡眠时长与内脏脂肪量积累呈负相关，每天睡眠超过8小时可能并无益处。需要进行机制性和前瞻性研究来证实睡眠时长对内脏肥胖的影响并确定其原因。
