Center for Weight and Eating Disorders, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, 3535 Market Street, Suite 3029, Philadelphia, PA, 19104-3309, USA.
Department of Psychology, University of Michigan, Ann Arbor, MI, 48109, USA.
Curr Obes Rep. 2024 Jun;13(2):203-213. doi: 10.1007/s13679-024-00570-3. Epub 2024 May 22.
Insomnia and short sleep have been linked with weight gain and obesity. However, these findings have not been consistent across studies. We review recent evidence for the association between insomnia, short sleep, and weight gain, as well as the relationship between behavioral and pharmacological treatments for sleep and weight.
The relationship between insomnia and obesity is mixed, with stronger associations between insomnia with short sleep and obesity than other presentations of insomnia. Short sleep is associated with weight gain. Z-drugs and benzodiazapines do not appear to impact weight, but many antidepressants and antipsychotics that are used for insomnia treatment do cause weight gain. The relationships between insomnia and short sleep with weight gain and obesity are inconsistent. More prospective trials are needed to identify mediators and moderators of this relationship to better develop and deliver effective interventions for both sleep and weight problems.
失眠和睡眠不足与体重增加和肥胖有关。然而，这些发现并非在所有研究中都一致。我们综述了最近关于失眠、睡眠不足与体重增加之间关联的证据，以及睡眠和体重的行为和药物治疗之间的关系。
失眠与肥胖的关系是复杂的，与短睡眠相关的失眠与肥胖的关联比其他失眠表现更强。睡眠不足与体重增加有关。Z 类药物和苯二氮䓬类药物似乎不会影响体重，但许多用于治疗失眠的抗抑郁药和抗精神病药确实会导致体重增加。失眠和短睡眠与体重增加和肥胖之间的关系不一致。需要更多的前瞻性试验来确定这种关系的中介和调节因素，以便更好地开发和提供睡眠和体重问题的有效干预措施。
