Dartmouth College, Hanover, NH, USA Moore Hall 3 Maynard St, Hanover, NH 03755, USA.
Dartmouth College, Hanover, NH, USA Moore Hall 3 Maynard St, Hanover, NH 03755, USA.
Cortex. 2023 May;162:56-64. doi: 10.1016/j.cortex.2023.01.012. Epub 2023 Mar 9.
COVID-19 can cause psychological problems including loss of smell and taste, long-lasting memory, speech, and language impairments, and psychosis. Here, we provide the first report of prosopagnosia following symptoms consistent with COVID-19. Annie is a 28-year-old woman who had normal face recognition prior to contracting COVID-19 in March 2020. Two months later, she noticed face recognition difficulties while experiencing symptom relapses and her deficits with faces have persisted. On two tests of familiar face recognition and two tests of unfamiliar face recognition, Annie showed clear impairments. In contrast, she scored normally on tests assessing face detection, face identity perception, object recognition, scene recognition, and non-visual memory. Navigational deficits frequently co-occur with prosopagnosia, and Annie reports that her navigational abilities are substantially worse than before she became ill. Self-report survey data from 54 respondents with long COVID showed that a majority reported reductions in visual recognition and navigation abilities. In summary, Annie's results indicate that COVID-19 can produce severe and selective neuropsychological impairments similar to deficits seen following brain damage, and it appears that high-level visual impairments are not uncommon in people with long COVID.
COVID-19 可导致心理问题，包括嗅觉和味觉丧失、长期记忆、言语和语言障碍以及精神病。在这里，我们首次报告了 COVID-19 后出现的面容失认症。Annie 是一名 28 岁的女性，她在 2020 年 3 月感染 COVID-19 之前的人脸识别功能正常。两个月后，她在经历症状复发时注意到人脸识别困难，并且她的面部缺陷一直持续存在。在两项熟悉的人脸识别测试和两项不熟悉的人脸识别测试中，Annie 表现出明显的障碍。相比之下，她在测试面部检测、面部身份感知、物体识别、场景识别和非视觉记忆方面的得分正常。导航障碍经常与面容失认症同时发生，Annie 报告说她的导航能力比生病前差得多。来自 54 名长 COVID 患者的自我报告调查数据显示，大多数患者报告视觉识别和导航能力下降。总的来说，Annie 的结果表明，COVID-19 可导致严重和选择性的神经心理学障碍，类似于大脑损伤后的缺陷，并且长 COVID 患者中似乎常见高级视觉障碍。
