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[脊柱恶性骨肿瘤的治疗策略]

[Treatment strategy of malignant bone tumors of the spine].

作者信息

Ritschl P, Eyb R, Samec P, Lack W, Kotz R

机构信息

Orthopädische Universitätsklinik, Universität Wien.

出版信息

Orthopade. 1987 Sep;16(5):379-88.

PMID:3696719
Abstract

In patients with big, tumorous changes in the vertebral bodies, conservative measures like radiotherapy, medical therapy, and external support measures are often no longer applicable. As a result of the instability of the spinal column, most of the patients are bedridden and in great pain. Signs of root compression occur frequently, as do incipient or incomplete transverse lesions. On the one hand, these signs result from tumor growth and on the other from collapse of the vertebral bodies with kyphosis and fragment dislocation in the spinal canal. In these patients the procedure of choice is "ventral" tumor removal, decompression of the spinal cord and roots, followed by stabilization. By the "dorsal" operative method, it is not possible to overcome the major cause of the instability and pain. On the basis of the results obtained in 100 "ventral" resections of the vertebral bodies, the treatment strategy is presented, ranging from the preliminary examination to the postoperative period.

摘要

对于椎体出现巨大肿瘤样改变的患者,放疗、药物治疗及外部支撑措施等保守治疗方法往往不再适用。由于脊柱不稳定,大多数患者只能卧床,疼痛剧烈。神经根受压症状频繁出现,早期或不完全性横贯性损伤也很常见。一方面,这些症状是肿瘤生长所致,另一方面是椎体塌陷、脊柱后凸以及椎管内碎骨片移位所致。对于这些患者,首选的治疗方法是“前路”肿瘤切除、脊髓和神经根减压,随后进行固定。采用“后路”手术方法无法解决导致不稳定和疼痛的主要问题。基于100例椎体“前路”切除术的结果,本文介绍了从术前检查到术后阶段的治疗策略。

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