Gibelalde Ane, Pinar-Sueiro Sergio, Ibarrondo Oliver, Martínez-Soroa Itziar, Mendicute Javier, Ruiz Miguel Miguel
Department of Ophthalmology, Donostia University Hospital, Paseo del Dr Beguiristain sn. San Sebastian, 20014, Donostia San-Sebastian, Gipuzkoa, Spain.
AP-OSI Research Unit, Alto Deba Integrated Health Care Organization, Mondragon, Spain.
Int J Retina Vitreous. 2023 Mar 26;9(1):17. doi: 10.1186/s40942-023-00455-y.
Given differences in the pathogenic mechanisms underlying primary retinal detachment (RD) as a function of the status of the lens, the objective was to explore differences between pseudophakic and phakic patients with primary RD.
A retrospective study including 821 patients who underwent surgery for RD [491 cases of phakic and 330 of pseudophakic RD (pRD and psRD, respectively)] in our hospital between 2012 and 2020.
The mean age was 58.24 ± 12.76 years in the pRD group and 66.87 ± 11.18 years in the psRD group (p = 0.001). There were more men in both groups (70% and 64.23% of pseudophakic and phakic patients, respectively; p = 0.07). The most common location for the RD was superior in both groups (43.94% and 51.93% of pseudophakic and phakic patients, respectively), rates of inferior and total RD were somewhat higher in the psRD group (31.82% and 13.33% in pseudophakic vs 25.25% and 11.0% in phakic patients, p = 0.001). In pseudophakic and phakic patients respectively, macular involvement in 69.09% and 62.73% of cases (p = 0.067). Proliferative vitreoretinopathy was significantly more common in the psRD group (7.88% vs 3.6% in phakic patients, p = 0.01).The rate of final anatomic reattachment differed markedly between groups, with a higher rate in phakic (94.03%) than pseudophakic (87.27%) patients (p = 0.001).
The specific pathogenic mechanism involved in psRD seems to be responsible for worse evolution characteristics which are associated with poorer final anatomic and functional outcomes in pseudophakic patients.
鉴于原发性视网膜脱离（RD）的致病机制因晶状体状态而异，目的是探讨原发性RD的人工晶状体眼和有晶状体眼患者之间的差异。
一项回顾性研究，纳入了2012年至2020年间在我院接受RD手术的821例患者[分别为491例有晶状体眼RD和330例人工晶状体眼RD（分别为pRD和psRD）]。
pRD组的平均年龄为58.24±12.76岁，psRD组为66.87±11.18岁（p = 0.001）。两组男性均较多（人工晶状体眼和有晶状体眼患者分别占70%和64.23%；p = 0.07）。两组RD最常见的部位均为上方（人工晶状体眼和有晶状体眼患者分别占43.94%和51.93%），psRD组下方和全RD的发生率略高（人工晶状体眼患者分别为31.82%和13.33%，有晶状体眼患者为25.25%和11.0%，p = 0.001）。人工晶状体眼和有晶状体眼患者黄斑受累分别为69.09%和62.73%（p = 0.067）。增生性玻璃体视网膜病变在psRD组明显更常见（有晶状体眼患者为7.88%，而有晶状体眼患者为3.6%，p = 0.01）。两组最终解剖复位率差异显著，有晶状体眼患者（94.03%）高于人工晶状体眼患者（87.27%）（p = 0.001）。
psRD涉及的特定致病机制似乎是导致其较差演变特征的原因，这与人工晶状体眼患者较差的最终解剖和功能结局相关。
