Alovisi Camilla, Panico Claudio, de Sanctis Ugo, Eandi Chiara M
Eye Trauma Center, Department of Ophthalmology, Turin Eye Hospital, Turin, Italy.
Department of Surgical Sciences, Eye Clinic, University of Turin, Turin, Italy.
J Ophthalmol. 2017;2017:3172138. doi: 10.1155/2017/3172138. Epub 2017 Jul 13.
Recent developments in vitreoretinal surgery have increased the need for suitable vitreous substitutes. A successful substitute should maintain all the physical and biochemical properties of the original vitreous, be easy to manipulate, and be long lasting. Substitutes can be gaseous or liquid, both of which have associated advantages and disadvantages related to their physical properties and use. Furthermore, new surgical techniques with smaller vitreoretinal instruments have driven the use of more viscous substitutes. In this review, we analyze and discuss the most frequently used vitreous substitutes and look ahead to future alternatives. We classify these compounds based on their composition and structure, discuss their clinical use with respect to their associated advantages and disadvantages, and analyze how new vitreoretinal surgical techniques have modified their use.
玻璃体视网膜手术的最新进展增加了对合适玻璃体替代物的需求。一种成功的替代物应保持原始玻璃体的所有物理和生化特性,易于操作且持久耐用。替代物可以是气态或液态,两者因其物理特性和用途都有相关的优缺点。此外,使用更小的玻璃体视网膜器械的新手术技术推动了更具粘性的替代物的使用。在本综述中,我们分析和讨论了最常用的玻璃体替代物,并展望了未来的替代物。我们根据这些化合物的组成和结构对其进行分类,讨论它们在临床使用中的相关优缺点,并分析新的玻璃体视网膜手术技术如何改变了它们的使用方式。