Li Xuefei, Chen Wenhua, Chen Qian, Li Fangfang, Chen Chen, Li Pan, Li Fangyu, Guo Suxia, Chen Pinghua, Yuan Weina, Liu Dan, Wang Shiyun, Hu Zhijun
Longhua Clinical Medical College of Shanghai University of Traditional Chinese Medicine, Shanghai, China.
School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Front Med (Lausanne). 2023 Mar 9;10:1135063. doi: 10.3389/fmed.2023.1135063. eCollection 2023.
This study aimed to use meta-analysis to determine the impact of resistance and balance training on athletic ability and quality of life for patients with osteoporotic vertebral fracture (OVF).
This study followed the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) criteria for systematic reviews and meta-analyzes. The PubMed, Web of science, Cochrane, Embase, and CNKI databases were searched for randomized controlled trials (RCTs) up to September 2022. The search strategy was related to the intervention measures, population, and results, and was structured around the search terms: "Exercise," "Osteoporotic vertebral fracture," and "activities of function." Two reviewers strictly implemented the inclusion and exclusion criteria. Subgroup analyzes of age and training duration were performed for the main outcomes.
We included 12 RCTs ( = 1,289) of resistance and balance training in patients with OVF. Compared with controls, the intervention group showed improvements on the Quality of Life Questionnaire issued by the European Foundation for Osteoporosis, visual analog pain scale, Timed Up and Go, falls efficacy scale international (FES-I), kyphosis, and functional reach. On subgroup analysis, the effect was more significant when training continued >10 weeks.
Resistance and balance exercise training improved function and balance, and reduced fall risk in patients with OVF. We recommend resistance and balance training for at least 10 weeks. Future multicenter, large sample trials are needed for more reliable conclusions.
本研究旨在通过荟萃分析确定抗阻和平衡训练对骨质疏松性椎体骨折（OVF）患者运动能力和生活质量的影响。
本研究遵循系统评价和荟萃分析的首选报告项目（PRISMA）标准进行系统评价和荟萃分析。检索了截至2022年9月的PubMed、科学网、Cochrane、Embase和中国知网数据库，以查找随机对照试验（RCT）。检索策略与干预措施、人群和结果相关，并围绕检索词“运动”、“骨质疏松性椎体骨折”和“功能活动”构建。两名评审员严格执行纳入和排除标准。对主要结局进行年龄和训练持续时间的亚组分析。
我们纳入了12项关于OVF患者抗阻和平衡训练的RCT（n = 1289）。与对照组相比，干预组在欧洲骨质疏松症基金会发布的生活质量问卷、视觉模拟疼痛量表、定时起立行走测试、国际跌倒效能量表（FES-I）、脊柱后凸和功能性伸展方面均有改善。亚组分析显示，训练持续时间>10周时效果更显著。
抗阻和平衡运动训练改善了OVF患者的功能和平衡，降低了跌倒风险。我们建议进行至少10周的抗阻和平衡训练。未来需要开展更多多中心、大样本试验以得出更可靠的结论。
