Tagliaferri Ariana R, Ansari Nida, Cavanagh Yana
Internal Medicine, St. Joseph's Regional Medical Center, Paterson, USA.
Gastroenterology, St. Joseph's Regional Medical Center, Paterson, USA.
Cureus. 2023 Feb 20;15(2):e35224. doi: 10.7759/cureus.35224. eCollection 2023 Feb.
Gallbladder agenesis is a rare congenital anomaly of the biliary tract, due to failure of the gallbladder and cystic duct budding off of the common bile duct during fetal development. Cholangiocarcinoma (CCA) is a malignant tumor arising from the biliary ducts in patients with underlying chronic biliary tract inflammation, primary sclerosing cholangitis, or other diseases. Although few studies have reported cases of cholelithiasis in patients with congenital gallbladder agenesis, there is only one other known case of concomitant cholangiocarcinoma and congenital gallbladder agenesis. Herein we present a case of recurrent gallstones in a male, diagnosed with gallbladder agenesis intraoperatively and with pathology consistent with cholangiocarcinoma.
胆囊缺如是一种罕见的先天性胆道异常，是由于在胎儿发育过程中胆囊和胆囊管未能从胆总管上芽生所致。胆管癌（CCA）是一种源于胆管的恶性肿瘤，发生于患有潜在慢性胆道炎症、原发性硬化性胆管炎或其他疾病的患者。尽管很少有研究报道先天性胆囊缺如患者发生胆石症的病例，但已知仅有另一例胆管癌与先天性胆囊缺如并存的病例。在此，我们报告一例男性复发性胆结石病例，术中诊断为胆囊缺如，病理结果符合胆管癌。
