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胆囊缺如:在成为令人不快的腹腔镜意外发现之前做出诊断——临床病例报告及文献综述

Agenesis of gall bladder: Diagnosed before it is an unpleasant laparoscopic surprise-clinical case report and review.

作者信息

Agarwal Puneet K

机构信息

Department of Surgery, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, 462020, India.

出版信息

Int J Surg Case Rep. 2020;76:144-147. doi: 10.1016/j.ijscr.2020.09.140. Epub 2020 Sep 23.

Abstract

INTRODUCTION & BACKGROUND: Agenesis of gall bladder is a rare congenital anomaly and incidence is 0.007-0.0027%. Even though gall bladder is absent, clinical presentation of 50% cases, mimic biliary colic. This combined with inconclusive radiological findings leads to wrong preoperative diagnosis and patients are subjected to unnecessary surgery causing complications like injury to biliary tract. Except for few cases where a preoperative diagnosis of absent gall bladder was made in majority of cases, agenesis of the gallbladder is described as an incidental finding during surgery. The work has been reported in line with the SCARE criteria (Agha et al., 2018).

CASE PRESENTATION

This article will share our experience about two cases who presented with complains of pain in right upper quadrant and USG examination revealed inconclusive reports as cholelethiasis with contracted or shrunken gall bladder in first case and in second case as cholelethiasis with non-visualisation of gall bladder. On further imaging with MR cholangiogram diagnosis of agenesis of gall bladder was made and unnecessary surgery was avoided.

DISCUSSION

Ultrasound is the imaging technique of choice to assess the gallbladder; but difficulty arises when gallbladder is either contracted or atrophic. Magnetic cholangioresonance is a non-invasive modality which can describe anatomy of biliary apparatus. So Magnetic cholangiogram should be combined with inconclusive USG studies for gall bladder agenesis.

CONCLUSION

With better imaging modalities, it has been possible to diagnose gallbladder agenesis before surgery. And so inconclusive US reports of gall bladder should be combined with MR imaging. In Perioperative scenario on suspicion of gall bladder agenesis present norm is to quit laparoscopy and resort to MR cholangiogram to reduce exploration complications.

摘要

引言与背景

胆囊缺如是一种罕见的先天性异常,发病率为0.007 - 0.0027%。即使没有胆囊,50%的病例临床表现类似胆绞痛。这与不确定的影像学检查结果相结合,导致术前诊断错误,患者接受不必要的手术,从而引发诸如胆道损伤等并发症。除少数病例术前诊断为胆囊缺如外,大多数情况下胆囊缺如是在手术中偶然发现的。本研究已按照SCARE标准(Agha等人,2018年)进行报告。

病例介绍

本文将分享我们对两例患者的经验。第一例患者主诉右上腹疼痛,超声检查结果不明确,提示为胆囊炎伴胆囊收缩或萎缩;第二例患者超声检查提示为胆囊炎伴胆囊未显影。通过磁共振胆胰管造影进一步成像后,诊断为胆囊缺如,避免了不必要的手术。

讨论

超声是评估胆囊的首选成像技术;但当胆囊收缩或萎缩时,诊断会出现困难。磁共振胆胰管造影是一种非侵入性检查方法,可描述胆道系统的解剖结构。因此,对于胆囊缺如,磁共振胆胰管造影应与不确定的超声检查结果相结合。

结论

随着成像技术的不断进步,术前诊断胆囊缺如已成为可能。因此,超声检查结果不明确的胆囊病例应结合磁共振成像检查。在围手术期,怀疑胆囊缺如时,通常的做法是停止腹腔镜检查,采用磁共振胆胰管造影,以减少探查并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8ce/7551974/fcbf3676c21b/gr1.jpg

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