Che Rahim Mohd Jazman, Abdull Wahab Shaik Farid, Fauzi Mohd Hashairi, Nadarajan Chandran, Ab Hamid Siti Azrin
School of Medical Sciences, Universiti Sains Malaysia - Kampus Kesihatan, Kelantan, Malaysia.
Hospital Universiti Sains Malaysia, Kelantan, Malaysia.
Ultrasound. 2022 Nov;30(4):292-298. doi: 10.1177/1742271X211051767. Epub 2021 Oct 17.
Contrast-enhanced ultrasonography (CEUS) using saline was studied to detect supradiaphragmatic central venous catheter malposition. Commonly used echocardiographic views are apical 4-chamber (A4c) and subcostal views. However, this standard method is not feasible in certain situations. We explored the feasibility of the right ventricle inflow parasternal long axis (RVI-PLAX) echocardiographic view and dextrose 50% (D50%) contrast solution for detecting supradiaphragmatic central venous catheter malposition.
This pilot study screened 60 patients who underwent ultrasound-guided supradiaphragmatic central venous catheter insertion. We compared the investigators' guidewire's J-tip detection, D50% rapid atrial swirl sign (RASS) findings on the RVI-PLAX view and the central venous catheter tip on chest radiograph. We also compared the mean capillary blood sugar level before and after the 5 ml D50% flush.
No guidewire J-tips were detected from the RVI-PLAX view. The first and second investigators' diagnosis of central venous catheter malposition detected on RVI-PLAX CEUS achieved an almost perfect agreement (κ = 1.0 (95% confidence interval (CI): 0.90 to 1.0), < .0001). The RVI-PLAX CEUS was not able to detect two central venous catheter malpositions (one atrial malposition and one left brachiocephalic vein venous catheter malposition). The capillary blood sugar was significantly elevated (8.96 mmol/L vs. 9.75 mmol/L) after D50% flush ( < 0.005) with no complications reported within 30 minutes after the D50% flush.
RVI-PLAX view should not be used for guidewire detection. CEUS using D50% and RVI-PLAX view are potentially useful tools in detecting central venous catheter malposition. Further studies comparing them with conventional methods are needed.
研究了使用生理盐水的超声造影(CEUS)以检测膈上中心静脉导管位置异常。常用的超声心动图切面是心尖四腔心(A4c)和肋下切面。然而,这种标准方法在某些情况下不可行。我们探讨了右心室流入道胸骨旁长轴(RVI-PLAX)超声心动图切面和50%葡萄糖(D50%)造影剂检测膈上中心静脉导管位置异常的可行性。
这项前瞻性研究筛选了60例行超声引导下膈上中心静脉导管置入术的患者。我们比较了研究人员的导丝J形尖端检测、RVI-PLAX切面上的D50%快速心房漩涡征(RASS)结果以及胸部X线片上的中心静脉导管尖端位置。我们还比较了5ml D50%冲洗前后的平均毛细血管血糖水平。
在RVI-PLAX切面上未检测到导丝J形尖端。第一位和第二位研究人员通过RVI-PLAX CEUS对中心静脉导管位置异常的诊断达成了几乎完美的一致性(κ = 1.0(95%置信区间(CI):0.90至1.0),P <.0001)。RVI-PLAX CEUS未能检测到两例中心静脉导管位置异常(一例心房位置异常和一例左头臂静脉导管位置异常)。D50%冲洗后毛细血管血糖显著升高(8.96 mmol/L对9.75 mmol/L)(P <0.005),D50%冲洗后30分钟内未报告并发症。
RVI-PLAX切面不应用于导丝检测。使用D50%的CEUS和RVI-PLAX切面是检测中心静脉导管位置异常的潜在有用工具。需要进一步研究将它们与传统方法进行比较。