Feng Le-Le, Du Jie, Wang Chen, Wang Shui-Li
Department of Respiratory and Critical Care Medicine I, Shaanxi Provincial People's Hospital, Xi'an 710068, Shaanxi Province, China.
Department of Respiratory and Critical Care Medicine I, Xi'an Medical University, Xi'an 710068, Shaanxi Province, China.
World J Clin Cases. 2023 Mar 16;11(8):1823-1829. doi: 10.12998/wjcc.v11.i8.1823.
Primary membranous nephrotic syndrome with chylothorax as the first manifestation is an unusual condition. To date, only a few cases have been reported in clinical practice.
The clinical data of a 48-year-old man with primary nephrotic syndrome combined with chylothorax admitted to the Department of Respiratory and Critical Care Medicine of Shaanxi Provincial People's Hospital were retrospectively analysed. The patient was admitted to the hospital for 12 d due to shortness of breath. Imaging showed pleural effusion, laboratory tests confirmed true chylothorax, and renal biopsy revealed membranous nephropathy. After primary disease treatment and early active symptom treatment, the prognosis of the patient was good. This case suggests that chylothorax is a rare complication of primary membranous nephrotic syndrome in adults, and early lymphangiography and renal biopsy can assist in the diagnosis when there are no contraindications.
Primary membranous nephrotic syndrome combined with chylothorax is rare in clinical practice. We report a relevant case to provide case information for clinicians and to improve diagnosis and treatment.
以乳糜胸为首发表现的原发性膜性肾病综合征是一种罕见的病症。迄今为止，临床实践中仅有少数病例报道。
回顾性分析了一名48岁原发性肾病综合征合并乳糜胸患者的临床资料，该患者入住陕西省人民医院呼吸与危重症医学科。患者因气短入院12天。影像学检查显示胸腔积液，实验室检查确诊为真性乳糜胸，肾活检显示为膜性肾病。经过原发性疾病治疗及早期积极的症状治疗，患者预后良好。该病例提示，乳糜胸是成人原发性膜性肾病综合征罕见的并发症，在无禁忌证时，早期淋巴管造影和肾活检有助于诊断。
原发性膜性肾病综合征合并乳糜胸在临床实践中较为罕见。我们报告了一例相关病例，为临床医生提供病例信息，以提高诊断和治疗水平。
