Petersen Johannes, Alassar Yousuf, Yildirim Yalin, Tönnis Tobias, Reichenspurner Hermann, Pecha Simon
Department of Cardiovascular Surgery, University Heart and Vascular Center Hamburg, Hamburg, Germany.
German Center for Cardiovascular Research (DZHK), Hamburg/Kiel/lübeck, Germany.
Front Cardiovasc Med. 2023 Mar 10;10:1129410. doi: 10.3389/fcvm.2023.1129410. eCollection 2023.
Atrial fibrillation (AF) is common in patients with heart failure resulting in a high prevalence of AF in patients receiving Cardiac Resynchronization Therapy (CRT) implantation. In patients, unsuitable for transvenous left ventricular (LV)-lead implantation, epicardial LV-lead implantation represents a valuable alternative. Epicardial LV-lead placement can be achieved totally thoracoscopical or minimally invasive left lateral thoracotomy. In patients with atrial fibrillation, concomitant left atrial appendage (LAA) clipping is feasible the same access. Therefore, the aim of our study was the analysis of safety and efficacy of epicardial LV lead implantation and concomitant LAA clipping minimally invasive left-lateral thoracotomy.
Between December 2019 and March 2022, 8 patients received minimally invasive left atrial LV-lead implantation with concomitant LAA closure using the AtriClip. Transesophageal echocardiography (TEE) was performed to intraoperatively guide and control LAA closure.
Mean patients age was 64 ± 11.2 years, 67% were male patients. Minimally invasive left-lateral thoracotomy was used in 6 patients while a totally thoracoscopic approach was performed in 2 cases. Epicardial lead implantation was successfully performed in all patients with good pacing threshold (mean 0.8 ± 0.2 V) and sensing values (10.1 ± 2.3 mV). Posterolateral position of the LV lead was achieved in all patients. Furthermore, successful LAA closure was confirmed during TEE in all patients. No procedure-related complications occurred in any of the patients. Two patients additionally received simultaneous laser lead extraction during the same procedure. Complete lead extraction was achieved in both patients. All patients were extubated in the OR and had an uneventful postoperative course.
Our study highlights a novel treatment approach for patients with atrial fibrillation and the necessity of epicardial LV leads. Placement of a posterolateral LV lead position with concomitant occlusion of the left atrial appendage a minimally-invasive left-lateral thoracotomy or even a totally thoracoscopic approach is safe and feasible with superior cosmetic result and complete occlusion of the left atrial appendage.
心房颤动(AF)在心力衰竭患者中很常见,导致接受心脏再同步治疗(CRT)植入的患者中AF患病率很高。对于不适合经静脉植入左心室(LV)导线的患者,心外膜LV导线植入是一种有价值的替代方法。心外膜LV导线放置可以通过完全胸腔镜或微创左外侧胸廓切开术实现。在心房颤动患者中,通过相同的入路同时进行左心耳(LAA)夹闭是可行的。因此,我们研究的目的是分析通过微创左外侧胸廓切开术进行心外膜LV导线植入并同时进行LAA夹闭的安全性和有效性。
2019年12月至2022年3月期间,8例患者接受了使用AtriClip进行的微创左心房LV导线植入并同时关闭LAA。术中采用经食管超声心动图(TEE)指导和控制LAA关闭。
患者平均年龄为64±11.2岁,67%为男性患者。6例患者采用微创左外侧胸廓切开术,2例采用完全胸腔镜手术。所有患者均成功进行了心外膜导线植入,起搏阈值良好(平均0.8±0.2V),感知值(10.1±2.3mV)。所有患者的LV导线均置于后外侧位置。此外,所有患者在TEE检查中均证实LAA成功关闭。所有患者均未发生与手术相关的并发症。2例患者在同一手术过程中还同时接受了激光导线拔除。两名患者均成功完成导线拔除。所有患者均在手术室拔管,术后过程顺利。
我们的研究突出了一种针对心房颤动患者的新治疗方法以及心外膜LV导线的必要性。通过微创左外侧胸廓切开术甚至完全胸腔镜手术将LV导线置于后外侧位置并同时闭塞左心耳是安全可行的,具有良好的美容效果且能完全闭塞左心耳。