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A Prospective Cohort Study of COVID-19: Evaluation of the Early Role of IL-1 and IL-6 Antagonists in Improving the Outcome of the Illness and Reduction in the Risk of Death.一项关于COVID-19的前瞻性队列研究:评估白细胞介素-1和白细胞介素-6拮抗剂在改善疾病预后及降低死亡风险方面的早期作用。
Healthcare (Basel). 2023 Apr 3;11(7):1025. doi: 10.3390/healthcare11071025.

本文引用的文献

1
Factors associated with mortality in patients with COVID-19 admitted to intensive care: a systematic review and meta-analysis.与 COVID-19 重症患者死亡率相关的因素:系统评价和荟萃分析。
Anaesthesia. 2021 Sep;76(9):1224-1232. doi: 10.1111/anae.15532. Epub 2021 Jun 29.
2
COVID-19 and indirect health implications in Africa: Impact, mitigation measures, and lessons learned for improved disease control.COVID-19 和非洲的间接健康影响:影响、缓解措施以及改善疾病控制的经验教训。
PLoS Med. 2021 Jun 23;18(6):e1003666. doi: 10.1371/journal.pmed.1003666. eCollection 2021 Jun.
3
Global Incidence of Neurological Manifestations Among Patients Hospitalized With COVID-19-A Report for the GCS-NeuroCOVID Consortium and the ENERGY Consortium.全球因 COVID-19 住院的患者的神经学表现发生率——GCS-NeuroCOVID 联盟和 ENERGY 联盟的报告。
JAMA Netw Open. 2021 May 3;4(5):e2112131. doi: 10.1001/jamanetworkopen.2021.12131.
4
Causes and timing of death in critically ill COVID-19 patients.危重症新冠肺炎患者的死亡原因及时间
Crit Care. 2021 Feb 23;25(1):79. doi: 10.1186/s13054-021-03492-x.
5
Hematological Abnormalities in COVID-19: A Narrative Review.新型冠状病毒肺炎相关血液学异常:一项叙述性综述。
Am J Trop Med Hyg. 2021 Feb 19;104(4):1188-1201. doi: 10.4269/ajtmh.20-1536.
6
Variation in US Hospital Mortality Rates for Patients Admitted With COVID-19 During the First 6 Months of the Pandemic.美国在大流行的前 6 个月中,因 COVID-19 入院的患者的医院死亡率存在差异。
JAMA Intern Med. 2021 Apr 1;181(4):471-478. doi: 10.1001/jamainternmed.2020.8193.
7
High Mortality Rate in Adult COVID-19 Inpatients in Eastern Sudan: A Retrospective Study.苏丹东部成人新冠肺炎住院患者的高死亡率:一项回顾性研究
J Multidiscip Healthc. 2020 Dec 8;13:1887-1893. doi: 10.2147/JMDH.S283900. eCollection 2020.
8
Risk factors for mortality in hospitalized patients with COVID-19: a study in Milan, Italy.意大利米兰一项关于新冠肺炎住院患者死亡风险因素的研究。
Infect Dis (Lond). 2021 Mar;53(3):226-229. doi: 10.1080/23744235.2020.1859131. Epub 2020 Dec 13.
9
Male sex identified by global COVID-19 meta-analysis as a risk factor for death and ITU admission.全球 COVID-19 荟萃分析显示,男性性别是死亡和 ICU 入院的风险因素。
Nat Commun. 2020 Dec 9;11(1):6317. doi: 10.1038/s41467-020-19741-6.
10
Risk factors for mortality in hospitalized patients with COVID-19 at the start of the pandemic in Belgium: a retrospective cohort study.大流行初期比利时住院 COVID-19 患者死亡的危险因素:一项回顾性队列研究。
BMC Infect Dis. 2020 Nov 27;20(1):897. doi: 10.1186/s12879-020-05605-3.

苏丹重症监护病房中新冠病毒疾病患者的结局:一项横断面研究。

The outcome of COVID-19 patients in the intensive care unit in Sudan: A cross-sectional study.

作者信息

Ali Mohammed A O, Abdalrahman Noon A, Shanab Elaf A I, Mohammed Mozan M A, Ibrahim Malaz M, Abdalrahman Ihab B

机构信息

Faculty of Medicine University of Khartoum Khartoum Sudan.

Faculty of Medicine Ahfad University for Women Omdurman Sudan.

出版信息

Health Sci Rep. 2023 Mar 22;6(3):e1161. doi: 10.1002/hsr2.1161. eCollection 2023 Mar.

DOI:10.1002/hsr2.1161
PMID:36970641
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10033838/
Abstract

BACKGROUND AND AIM

A major outbreak of coronavirus spread all over the world and gave rise to high mortality rate and high admission rate to intensive care unit (ICU). This cohort study aims to assess the outcome of COVID-19 patients in ICU and to investigate the factors associated with mortality.

METHOD

This is a multicentered retrospective cohort study that was conducted among confirmed cases of COVID-19 patients, who were admitted to ICU in Sudan during March 2021. The data collection was done manually from the medical records of patients. Mortality rate and association and prediction of factors associated with mortality were obtained using Statistical Package for the Social Sciences software (SPSS) version 22.

RESULTS

The mortality rate among patients in this study was 70%. Using the chi-square test we found that age, needing intubation, developing Systemic inflammatory response syndrome, neurological complications, hematological complications, and cardiac complications have a significant association with the outcome.

CONCLUSION

Majority of COVID-19 patients who were admitted to the ICU died. 55.8% of patients developed at least one complication during their stay in ICU. The age, the need for intubation, and developing of systematic inflammatory response syndrome (SIRS) are the factors that predict the mortality.

摘要

背景与目的

冠状病毒的一次大爆发在全球蔓延,导致了高死亡率和高重症监护病房(ICU)收治率。这项队列研究旨在评估ICU中COVID-19患者的结局,并调查与死亡率相关的因素。

方法

这是一项多中心回顾性队列研究,研究对象为2021年3月在苏丹入住ICU的COVID-19确诊患者。数据收集通过手动查阅患者病历完成。使用社会科学统计软件包(SPSS)22版得出死亡率以及与死亡率相关因素的关联和预测结果。

结果

本研究中患者的死亡率为70%。通过卡方检验,我们发现年龄、需要插管、发生全身炎症反应综合征、神经系统并发症、血液学并发症和心脏并发症与结局有显著关联。

结论

入住ICU的COVID-19患者大多数死亡。55.8%的患者在ICU住院期间至少出现一种并发症。年龄、插管需求以及全身炎症反应综合征(SIRS)的发生是预测死亡率的因素。