Ali Mohammed A O, Abdalrahman Noon A, Shanab Elaf A I, Mohammed Mozan M A, Ibrahim Malaz M, Abdalrahman Ihab B
Faculty of Medicine University of Khartoum Khartoum Sudan.
Faculty of Medicine Ahfad University for Women Omdurman Sudan.
Health Sci Rep. 2023 Mar 22;6(3):e1161. doi: 10.1002/hsr2.1161. eCollection 2023 Mar.
A major outbreak of coronavirus spread all over the world and gave rise to high mortality rate and high admission rate to intensive care unit (ICU). This cohort study aims to assess the outcome of COVID-19 patients in ICU and to investigate the factors associated with mortality.
This is a multicentered retrospective cohort study that was conducted among confirmed cases of COVID-19 patients, who were admitted to ICU in Sudan during March 2021. The data collection was done manually from the medical records of patients. Mortality rate and association and prediction of factors associated with mortality were obtained using Statistical Package for the Social Sciences software (SPSS) version 22.
The mortality rate among patients in this study was 70%. Using the chi-square test we found that age, needing intubation, developing Systemic inflammatory response syndrome, neurological complications, hematological complications, and cardiac complications have a significant association with the outcome.
Majority of COVID-19 patients who were admitted to the ICU died. 55.8% of patients developed at least one complication during their stay in ICU. The age, the need for intubation, and developing of systematic inflammatory response syndrome (SIRS) are the factors that predict the mortality.
冠状病毒的一次大爆发在全球蔓延,导致了高死亡率和高重症监护病房(ICU)收治率。这项队列研究旨在评估ICU中COVID-19患者的结局,并调查与死亡率相关的因素。
这是一项多中心回顾性队列研究,研究对象为2021年3月在苏丹入住ICU的COVID-19确诊患者。数据收集通过手动查阅患者病历完成。使用社会科学统计软件包(SPSS)22版得出死亡率以及与死亡率相关因素的关联和预测结果。
本研究中患者的死亡率为70%。通过卡方检验,我们发现年龄、需要插管、发生全身炎症反应综合征、神经系统并发症、血液学并发症和心脏并发症与结局有显著关联。
入住ICU的COVID-19患者大多数死亡。55.8%的患者在ICU住院期间至少出现一种并发症。年龄、插管需求以及全身炎症反应综合征(SIRS)的发生是预测死亡率的因素。