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新冠病毒肺炎住院患者的死亡率、重症监护病房收治率及插管率:约旦的一项为期一年的回顾性研究

Mortality, Intensive Care Unit Admission, and Intubation among Hospitalized Patients with COVID-19: A One-Year Retrospective Study in Jordan.

作者信息

Al Oweidat Khaled, Al-Amer Rasmieh, Saleh Mohammad Y, Albtoosh Asma S, Toubasi Ahmad A, Ribie Mona Khaled, Hasuneh Manar M, Alfaqheri Daniah L, Alshurafa Abdullah H, Ribie Mohammad, Ali Amira Mohammed, Obeidat Nathir

机构信息

Department of Respiratory and Sleep Medicine, Faculty of Medicine, The University of Jordan, Amman 11942, Jordan.

Department of Internal Medicine, Faculty of Medicine, The University of Jordan, Amman 11942, Jordan.

出版信息

J Clin Med. 2023 Apr 2;12(7):2651. doi: 10.3390/jcm12072651.

Abstract

COVID-19 is a public health crisis that has caused numerous deaths, necessitated an increased number of hospital admissions, and led to extended inpatient stays. This study aimed to identify the factors associated with COVID-19 mortality, intensive care unit admission, intubation, and length of hospital stay among Jordanian patients. This was a one-year retrospective study of 745 COVID-19 patients admitted to Jordan University Hospital. Data regarding the patients' demographics, clinical and co-morbid conditions, imaging, laboratory parameters, mortality, intensive care unit admission (ICU), and intubation were collected from their medical records using a coding manual. The data revealed that the overall rates of COVID-19-related mortality, ICU admission, and invasive intubation were 23.0%, 28.3%, and 10.8%, respectively. Chronic kidney disease (CKD), troponin, lactate dehydrogenase (LDH), and O saturation <90% were significantly associated with the mortality rate. The variables that were significantly associated with ICU admission were heart failure and the use of remdesivir. However, O saturation <90% and gastrointestinal (GI) symptoms were the only variables associated with invasive intubation. The findings of this study suggest that study-related health outcomes can be used to predict the severity of COVID-19, and they can inform future research aiming to identify specific populations who are at a higher risk of COVID-19 complications.

摘要

新冠病毒病(COVID-19)是一场公共卫生危机,已导致众多人死亡,使得住院人数增加,并导致住院时间延长。本研究旨在确定约旦患者中与COVID-19死亡率、重症监护病房收治、插管以及住院时间相关的因素。这是一项对约旦大学医院收治的745例COVID-19患者进行的为期一年的回顾性研究。使用编码手册从患者病历中收集有关患者人口统计学、临床和合并症情况、影像学、实验室参数、死亡率、重症监护病房收治(ICU)和插管的数据。数据显示,COVID-19相关死亡率、ICU收治率和有创插管率分别为23.0%、28.3%和10.8%。慢性肾脏病(CKD)、肌钙蛋白、乳酸脱氢酶(LDH)和氧饱和度<90%与死亡率显著相关。与ICU收治显著相关的变量是心力衰竭和使用瑞德西韦。然而,氧饱和度<90%和胃肠道(GI)症状是与有创插管相关的仅有的变量。本研究结果表明,与研究相关的健康结局可用于预测COVID-19的严重程度,并可为未来旨在确定COVID-19并发症风险较高的特定人群的研究提供信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff3f/10094820/82505e07c7c1/jcm-12-02651-g001.jpg

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