高效合成 3-巯基吲哚：HI 促进的吲哚与亚硫酸钠的磺酰化反应。
Efficient Synthesis of 3-Mercaptoindoles via HI-Promoted Sulfenylation of Indoles with Sodium Sulfinates.
机构信息
State Key Laboratory of NBC Protection for Civilian, 102205, Beijing, China.
出版信息
ChemistryOpen. 2023 Mar;12(3):e202300002. doi: 10.1002/open.202300002.
Abstract
A new direct sulfenylation method of indoles by sodium sulfinates and hydroiodic acid was developed giving variety of 3-sulfenylindoles in high yields under mild conditions without using any catalysts or other additives. In situ-generated RS-I species are supposed to be mainly responsible for the key electrophilic alkyl- or aryl-thiolation process.
摘要
发展了一种由亚硫酸钠和氢碘酸引发的吲哚的新型直接硫酚化方法，该方法在温和条件下无需使用任何催化剂或其他添加剂，以高产率得到了多种 3-硫代吲哚。推测原位生成的 RS-I 物种主要负责关键的亲电烷基化或芳基硫代化过程。
Zotero 插件