Biological Sciences, University of California Irvine, Irvine, CA, United States.
School of Pharmacy and Health Sciences, Keck Graduate Institute, Claremont, CA, United States.
Int J STD AIDS. 2023 Jul;34(8):512-517. doi: 10.1177/09564624231165547. Epub 2023 Mar 27.
Understanding the cost-effectiveness of the HPV vaccine from a global perspective is important to assess from a policy perspective and to support current and future HPV vaccination programs.
The aim of this analysis was to conduct a targeted literature review of published pharmacoeconomic literature on the cost-effectiveness of the HPV vaccine to treat patients in various countries, with a focus on cost-savings and their impact on vaccine recommendations.
We searched cost-effectiveness studies in HPV published in peer-reviewed literature from 2012 to 2020 using MEDLINE via the PubMed database and Google Scholar.
HPV vaccine cost-effectiveness was found to be greatest in low-income countries where screen programs were not yet in place, additionally, in adolescent males and females. The majority of the economic evaluations viewed the implementation of the HPV vaccine as cost-effective and recommended national HPV vaccination.
The majority of economic studies favored national HPV vaccination for adolescent males and females in various countries. Feasibility of this strategy and implementation remains an open question, in addition to screening coverage rate in countries with no vaccine programs or countries yet to introduce national HPV vaccination.
从全球视角了解 HPV 疫苗的成本效益对于从政策角度评估和支持当前和未来的 HPV 疫苗接种计划非常重要。
本分析旨在对已发表的 HPV 疫苗成本效益的药物经济学文献进行有针对性的文献回顾，重点关注成本节约及其对疫苗推荐的影响，这些文献针对来自不同国家的患者。
我们使用 MEDLINE 通过 PubMed 数据库和 Google Scholar 搜索了 2012 年至 2020 年发表的 HPV 疫苗成本效益的同行评审文献。
HPV 疫苗在尚未实施筛查计划的低收入国家以及青少年男性和女性中具有最大的成本效益。大多数经济评估认为实施 HPV 疫苗具有成本效益，并建议在各国接种 HPV 疫苗。
大多数经济研究都支持在不同国家为青少年男性和女性接种 HPV 疫苗。这种策略的可行性和实施仍然是一个悬而未决的问题，除了在没有疫苗计划的国家或尚未引入国家 HPV 疫苗接种的国家的筛查覆盖率之外。
