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初次单节段或双节段微创 versus 开放经椎间孔腰椎体间融合术后因邻近节段疾病导致的再次手术率。

Reoperation Rates Due to Adjacent Segment Disease Following Primary 1 to 2-Level Minimally Invasive Versus Open Transforaminal Lumbar Interbody Fusion.

机构信息

Department of Orthopedic Surgery, NYU Langone Orthopedic Hospital, New York City, NY.

出版信息

Spine (Phila Pa 1976). 2023 Sep 15;48(18):1295-1299. doi: 10.1097/BRS.0000000000004645. Epub 2023 Mar 23.

Abstract

STUDY DESIGN

Retrospective analysis of prospectively collected data.

OBJECTIVE

To investigate the effect of the approach of the transforaminal lumbar interbody fusion [TLIF; open vs . minimally invasive (MIS)] on reoperation rates due to ASD at 2 to 4-year follow-up.

SUMMARY OF BACKGROUND DATA

Adjacent segment degeneration is a complication of lumbar fusion surgery, which may progress to adjacent segment disease (ASD) and cause debilitating postoperative pain potentially requiring additional operative management for relief. MIS TLIF surgery has been introduced to minimize this complication but the impact on ASD incidence is unclear.

MATERIALS AND METHODS

For a cohort of patients undergoing 1 or 2-level primary TLIF between 2013 and 2019, patient demographics and follow-up outcomes were collected and compared among patients who underwent open versus MIS TLIF using the Mann-Whitney U test, Fischer exact test, and binary logistic regression.

RESULTS

Two hundred thirty-eight patients met the inclusion criteria. There was a significant difference in revision rates due to ASD between MIS and open TLIFs at 2 (5.8% vs . 15.4%, P =0.021) and 3 (8% vs . 23.2%, P =0.03) year follow-up, with open TLIFs demonstrating significantly higher revision rates. The surgical approach was the only independent predictor of reoperation rates at both 2 and 3-year follow-ups (2 yr, P =0.009; 3 yr, P =0.011).

CONCLUSIONS

Open TLIF was found to have a significantly higher rate of reoperation due to ASD compared with the MIS approach. In addition, the surgical approach (MIS vs . open) seems to be an independent predictor of reoperation rates.

摘要

研究设计

前瞻性收集数据的回顾性分析。

目的

探讨经椎间孔腰椎体间融合术(TLIF;开放与微创(MIS))入路对 2 至 4 年随访时因 ASD 再手术率的影响。

背景资料概要

腰椎融合术后邻近节段退变是一种并发症,可能进展为邻近节段疾病(ASD),并导致术后虚弱性疼痛,可能需要额外的手术治疗来缓解。MIS TLIF 手术的引入是为了最大限度地减少这种并发症,但对 ASD 发生率的影响尚不清楚。

材料和方法

对于 2013 年至 2019 年间接受 1 或 2 级原发性 TLIF 的患者队列,收集患者人口统计学和随访结果,并使用 Mann-Whitney U 检验、Fisher 确切检验和二元逻辑回归比较接受开放与 MIS TLIF 的患者。

结果

238 例患者符合纳入标准。MIS 和开放 TLIF 在 2 年(5.8%比 15.4%,P =0.021)和 3 年(8%比 23.2%,P =0.03)随访时因 ASD 再手术率存在显著差异,开放 TLIF 显示再手术率明显更高。手术入路是 2 年和 3 年随访时再手术率的唯一独立预测因素(2 年,P =0.009;3 年,P =0.011)。

结论

与 MIS 入路相比,开放 TLIF 因 ASD 再手术率明显更高。此外,手术入路(MIS 与开放)似乎是再手术率的独立预测因素。

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