Ermamilia Aviria, Aulia Bianda, Mulatsih Sri
Department of Nutrition and Health, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Department of Pediatrics, Faculty of Medicine, Public Health & Nursing, Universitas Gadjah Mada - Dr Sardjito Hospital, Yogyakarta, Indonesia.
Nutr Health. 2025 Mar;31(1):225-234. doi: 10.1177/02601060231166163. Epub 2023 Mar 27.
Adequate energy and protein intakes are required to maintain nutritional status and prevent clinical deterioration in paediatric oncology patients. There are limited investigations of malnutrition and dietary intake adequacy during treatment in developing countries. This study aimed to assess the nutritional status and macro- and micronutrient intake adequacy in paediatric oncology patients undergoing therapy. This cross-sectional study was conducted at Dr Sardjito Hospital, Indonesia. Sociodemographic, anthropometry, dietary intake, and anxiety status were collected. Patients were grouped based on cancer aetiology (haematological malignancy (HM) or solid tumour (ST). Variables between groups were compared. values of <0.05 were considered statistically significant. 82 patients aged 5-17 years (65.9% HM) were analysed. The prevalence of underweight was 24.4% (ST vs HM: 26.9% vs 23.2%), overweight 9.8% (ST vs HM: 11.5% vs 8.5%), and obesity 6.1% (ST vs HM: 0.0% vs 8.5%) according to BMI-for-age z-score. Mid-upper-arm circumference identified undernutrition in 55.7% and overnutrition in 3.7% of the patients. Stunted growth was found in 20.8% of the patients. Percentages of children with inadequate energy and protein intake were 43.9% and 26.8%, respectively. The percentages of participants meeting the national micronutrient requirements were low, ranging from 3.8% to 56.1%, with the highest adherence rate observed for vitamin A and the lowest for vitamin E. Appetite loss was associated with lower overall intake. This study confirmed that malnutrition is prevalent in paediatric patients treated for cancer. Inadequate intakes of macro- and micro-nutrients were also common, highlighting the need for early nutritional assessment and intervention.
维持小儿肿瘤患者的营养状况并防止临床病情恶化需要充足的能量和蛋白质摄入。在发展中国家,针对治疗期间营养不良和饮食摄入充足性的调查有限。本研究旨在评估接受治疗的小儿肿瘤患者的营养状况以及常量和微量营养素摄入充足性。这项横断面研究在印度尼西亚的萨迪托博士医院进行。收集了社会人口统计学、人体测量学、饮食摄入和焦虑状况等信息。患者根据癌症病因(血液系统恶性肿瘤(HM)或实体瘤(ST))进行分组。比较了组间变量。P值<0.05被认为具有统计学意义。对82名5至17岁的患者(65.9%为HM)进行了分析。根据年龄别BMI z评分,体重不足的患病率为24.4%(ST组与HM组:26.9%对23.2%),超重为9.8%(ST组与HM组:11.5%对8.5%),肥胖为6.1%(ST组与HM组:0.0%对8.5%)。上臂中部周长确定55.7%的患者存在营养不良,3.7%的患者存在营养过剩。20.8%的患者存在生长发育迟缓。能量和蛋白质摄入不足的儿童百分比分别为43.9%和26.8%。达到国家微量营养素需求的参与者百分比很低,在3.8%至56.1%之间,维生素A的依从率最高,维生素E的依从率最低。食欲减退与总体摄入量较低有关。本研究证实,接受癌症治疗的小儿患者中营养不良很普遍。常量和微量营养素摄入不足也很常见,这突出了早期营养评估和干预的必要性。