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将证据付诸实践:美国预防服务工作组制定预防服务建议方法的最新进展。

Putting Evidence Into Practice: An Update on the US Preventive Services Task Force Methods for Developing Recommendations for Preventive Services.

机构信息

Division of General Internal Medicine, Massachusetts General Hospital and Department of Medicine, Harvard Medical School, Boston, Massachusetts (Barry)

Agency for Healthcare Research and Quality, Rockville, Maryland (Wolff, Fan, Mabry-Hernandez, Mills).

出版信息

Ann Fam Med. 2023 Mar-Apr;21(2):165-171. doi: 10.1370/afm.2946.

Abstract

PURPOSE

The US Preventive Services Task Force (USPSTF) is an independent body that makes evidence-based recommendations regarding preventive services to improve health for people nationwide. Here, we summarize current USPSTF methods, describe how methods are evolving to address preventive health equity, and define evidence gaps for future research.

METHODS

We summarize current USPSTF methods as well as ongoing methods development.

RESULTS

The USPSTF prioritizes topics on the basis of disease burden, extent of new evidence, and whether the service can be provided in primary care and going forward will increasingly consider health equity. Analytic frameworks specify the key questions and linkages connecting the preventive service to health outcomes. Contextual questions provide information on natural history, current practice, health outcomes in high-risk groups, and health equity. The USPSTF assigns a level of certainty to the estimate of net benefit of a preventive service (high, moderate, or low). The magnitude of net benefit is also judged (substantial, moderate, small, or zero/negative). The USPSTF uses these assessments to assign a letter grade from A (recommend) to D (recommend against). I statements are issued when evidence is insufficient.

CONCLUSIONS

The USPSTF will continue to evolve its methods for simulation modeling and to use evidence to address conditions for which there are limited data for population groups who bear a disproportionate burden of disease. Additional pilot work is underway to better understand the relations of the social constructs of race, ethnicity, and gender with health outcomes to inform the development of a USPSTF health equity framework.

摘要

目的

美国预防服务工作组(USPSTF)是一个独立的机构,就全国范围内改善人民健康的预防服务提出基于证据的建议。在这里,我们总结了当前 USPSTF 的方法,描述了如何发展方法以解决预防保健公平问题,并为未来的研究定义了证据差距。

方法

我们总结了当前 USPSTF 的方法以及正在进行的方法开发。

结果

USPSTF 根据疾病负担、新证据的程度以及该服务是否可以在初级保健中提供,优先考虑主题,并将越来越多地考虑健康公平。分析框架指定了将预防服务与健康结果联系起来的关键问题和联系。背景问题提供了关于自然史、当前实践、高危人群的健康结果和健康公平的信息。USPSTF 对预防服务的净效益估计(高、中或低)的确定性水平进行分级。净效益的幅度也被判断(大量、中等、小或零/负)。USPSTF 使用这些评估来分配从 A(推荐)到 D(反对)的字母等级。当证据不足时,会发布 I 声明。

结论

USPSTF 将继续发展其模拟建模方法,并利用证据解决对疾病负担不成比例的人群的条件的数据有限的问题。正在进行额外的试点工作,以更好地了解种族、民族和性别等社会结构与健康结果的关系,为制定 USPSTF 健康公平框架提供信息。

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