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[儿童肠易激综合征]

[Irritable bowel syndrome in children].

作者信息

Ansaldi N, Villata L, Santini B, Fantino N, Robazza V, Ciervo T, Barbera C, Elia G, Oderda G

机构信息

Istituto di Discipline Pediatriche, Cattedra di Puericultura dell'Università di Torino, Italia.

出版信息

Pediatr Med Chir. 1987 Jul-Aug;9(4):453-9.

PMID:3697325
Abstract

The irritable bowel syndrome (IBS) is the most common chronic functional gastroenterological disorder both in adults and in children. In this study we evaluate the different aspects of this syndrome, comparing our observations on 332 children with other studies. Epidemiological data (frequency, sex, age) are examined so as the family histories of gastroenterological disorders. We take in account several pathogenic hypotheses, especially with reference to the alterations of gastrointestinal motility, which could be caused by several factors (psychological, prostaglandins, bile acids, etc.). The clinical picture is very variable, variations depending on the age of children and on the time of onset of IBS. The colic of neonate, caused by retention of air, is the main symptom in the first months of life, followed by chronic diarrhoea, also defined as toddler's diarrhoea, sometime alternating with constipation. In later childhood, recurrent abdominal pain represents a common complaint, in association with diarrhoea or constipation. The principal steps for a proper diagnosis so as the main differential diagnosis are defined. We explain the most important features of management (reassuring parents, free diet), excluding prescription of drugs, that produce only a transitory and symptomatic relief, so as elimination diets, that cause only a failure to thrive without any improvement of symptoms.

摘要

肠易激综合征(IBS)是成人和儿童中最常见的慢性功能性胃肠疾病。在本研究中,我们评估了该综合征的不同方面,并将我们对332名儿童的观察结果与其他研究进行了比较。我们研究了流行病学数据(发病率、性别、年龄)以及胃肠疾病的家族史。我们考虑了几种致病假说,特别是关于胃肠动力改变的假说,这些改变可能由多种因素(心理因素、前列腺素、胆汁酸等)引起。临床表现差异很大,其差异取决于儿童的年龄和肠易激综合征的发病时间。新生儿因空气潴留引起的绞痛是生命最初几个月的主要症状,随后是慢性腹泻,也称为幼儿腹泻,有时会与便秘交替出现。在儿童后期,反复腹痛是常见的主诉,常伴有腹泻或便秘。本文定义了正确诊断的主要步骤以及主要的鉴别诊断。我们解释了管理的最重要特征(安抚家长、自由饮食),不包括仅能产生暂时症状缓解的药物处方,以及只会导致发育不良而症状无任何改善的排除饮食。

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